›› 2011, Vol. 38 ›› Issue (7): 187-189.

• 疾病防治 • 上一篇    下一篇

硝唑尼特对四翼无刺线虫的驱虫效果

王泽东1, 马月1, 李文超1,2, 李伟志1, 孟莹1, 宫鹏涛1, 杨举1, 李建华1, 张西臣1   

  1. 1. 吉林大学畜牧兽医学院,吉林长春 130062;2. 安徽科技学院动物科学学院,安徽凤阳 233100
  • 收稿日期:1900-01-01 修回日期:2011-03-28 出版日期:2011-07-20 发布日期:2011-07-20
  • 通讯作者: 张西臣

Therapeutic Effect of Nitazoxanide on Aspiculuris tetraptera

WANG Ze-dong1, MA Yue1, LI Wen-chao1,2, LI Wei-zhi1, MENG Ying1, GONG Peng-tao1, YANG Ju1, LI Jian-hua1, ZHANG Xi-chen1   

  1. 1. College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China;2. College of Animal Science, Anhui Science and Technology University, Fengyang 233100, China
  • Received:1900-01-01 Revised:2011-03-28 Online:2011-07-20 Published:2011-07-20

摘要: 20只自然感染四翼无刺线虫的雌性昆明系小鼠,随机分成4组,每组5只,常规饲喂。第1~3组小鼠分别以200、400、800 mg/kg剂量的硝唑尼特灌胃,第4组设为空白对照组,每24 h一次,连续灌胃5 d。用虫卵减少率和粗计驱虫率作为评价药物效果的指标。结果显示,硝唑尼特对四翼无刺线虫的驱虫效果随药物剂量的增加而提高,以800 mg/kg剂量效果最好。

关键词: 硝唑尼特; 四翼无刺线虫; 小鼠

Abstract: Twenty mice infected with Aspiculuris tetraptera naturally were assigned randomly into four groups (n=5). GroupsⅠ-Ⅲ were fed with Nitazoxanide at a dosage of 200, 400, 800 mg/kg every 24 hours for 5 consecutive days, group Ⅳ with no treatment were used as the control. Faecal egg count reduction percentage and crude insecticide rate were used as the evaluation of drug effects of insecticide targets. The results showed that the insecticide effect of Nitazoxanide on Aspiculuris tetraptera increased with the increase of drug dose, and the dose of 800 mg/kg had the best effect.

Key words: Nitazoxanide; Aspiculuris tetraptera; mice

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