›› 2008, Vol. 1 ›› Issue (7): 49-51.

• 生理生化 • 上一篇    下一篇

动物多聚免疫球蛋白受体研究概况

张春刚1,2,王加启1,刘光磊1,程金波1,卜登攀1,赵国琦2   

  1. 1. 中国农业科学院北京畜牧兽医研究所 动物营养学国家重点实验室, 北京 100193;2. 扬州大学动物科学与技术学院, 扬州 225009
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-07-20 发布日期:2008-07-20

Research Overview on Animal Polymeric Immunoglobulin Receptor

ZHANG Chun-gang1,2, WANG Jia-qi1, LIU Guang-lei1, 
CHENG Jin-bo1, BU Deng-pan1, ZHAO Guo-qi2
  

  1. 1.State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Science, Beijing 100193, China;2.College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-07-20 Published:2008-07-20

摘要: 多聚免疫球蛋白受体(polymeric immunoglobulin receptor,pIgR)是主要组织相容性复合物(MHC)家族中的重要成员,是分泌性免疫系统(SIS)的重要组成成分,在IgA/IgM的转运和黏膜免疫中发挥着重要的作用。作者结合近年来的研究综述了pIgR的分子结构、生物学功能和研究概况。

关键词: pIgR/SC; IgA/IgM; 抗体转运; 黏膜免疫

Abstract: Polymeric immunoglobulin receptor (abbreviation as pIgR) is the key member of major histocompatibility complex (MHC) and secretory immune system (SIS). It plays an important role in IgA or IgM transportation and mucosa immune. This article summarizes the molecular structures, biological functions and research advances of pIgR based on recent researches.

Key words: pIgR/SC; IgA/IgM; antibody transportation; mucosa immune

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