富血小板血浆在马运动系统损伤中的应用研究进展

doi:10.16431/j.cnki.1671-7236.2024.04.045

摘要/Abstract

摘要： 马属动物尤其是运动马常发生运动系统损伤,损伤一旦发生,均会导致不同程度的跛行,且受损组织难以完全修复,常导致马运动性能大幅下降和不良预后,是运动马提前结束运动生涯最主要的原因之一。富血小板血浆(PRP)是一种再生医学制剂,通过激活血小板释放大量生长因子促进组织修复和再生。许多研究和临床报道表明,PRP对运动损伤有一定治疗效果,最常用于治疗马属动物肌腱、韧带损伤和骨关节炎,在欧美等国家应用较多。另外,PRP还具有一定抗菌效果,有望用于治疗感染性骨关节炎。对蹄叶炎等目前缺乏有效治疗药物的疾病也表现出一定的治疗潜力。在马运动医学领域,国内对PRP作用机制和应用范围了解较少,临床实践方面缺乏有关运用PRP治疗马运动系统损伤的研究报道。笔者从PRP制备和分类、PRP在治疗马运动系统损伤中的临床应用及研究进展进行综述,总结PRP在治疗马运动系统损伤中的应用范围和发展趋势,以期为国内兽医及相关从业人员应用PRP提供参考。

关键词: 马; 富血小板血浆; 运动系统损伤; 临床应用

Abstract: Equine,especially sport horses,tend to suffer from locomotor system injury.Once the injury occurs,it will lead to varying degrees of lameness,and it is difficult to completely repair the damaged tissue,which often leads to a significant decline in horse motor performance and poor prognosis,and is one of the main reasons for the early end of sports career of sports horses.Platelet-rich plasma (PRP) is a regenerative medicine formulation that promotes tissue repair and regeneration by activating platelets to release large amounts of growth factors.Many studies and clinical reports have shown that PRP has a certain therapeutic effect on locomotor injuries,and is most commonly used in the treatment of equine tendon,ligament injury and osteoarthritis,and is widely used in Europe and the United States and other countries.In addition,PRP also has certain antibacterial effect and is expected to be used in the treatment of septic arthritis.It also shows a certain therapeutic potential for laminitis and other diseases with limited response of traditional treatment.In the field of equine sports medicine,the mechanism and scope of application of PRP are not well understood in China,and there is a lack of research reports on the use of PRP in the treatment of equine locomotor system injury in clinical practice.The author reviewed the preparation and classification of PRP,the clinical application and research progress of PRP in the treatment of equine locomotor system injury,and summarized the application scope and development trend of PRP in the treatment of equine locomotor system injury,in order to provide references for domestic veterinarians and related practitioners to apply PRP.

Key words: equine; platelet-rich plasma; locomotor system injuries; clinical application

中图分类号:

S852.2

彭聪, 李靖, 汤小朋, 王子璇, 吴雨虹, 朱怡平. 富血小板血浆在马运动系统损伤中的应用研究进展[J]. 中国畜牧兽医, 2024, 51(4): 1784-1791.

PENG Cong, LI Jing, TANG Xiaopeng, WANG Zixuan, WU Yuhong, ZHU Yiping. Research Progress on the Application of Platelet-rich Plasma in the Equine Locomotor System Injuries[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(4): 1784-1791.

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