布拉迪酵母菌的生物学功能、作用机制及其应用

doi:10.16431/j.cnki.1671-7236.2020.08.015

摘要/Abstract

摘要： 布拉迪酵母是酿酒酵母的亚种，具有耐高温和耐胆盐的特性，通过改变病原菌的表面减少肠道致病菌。其分泌物能提高动物体内的酶活，从而促进营养物质的消化吸收；还能通过干扰促炎因子来提高机体抗炎作用。布拉迪酵母临床上可用于防治抗生素相关性腹泻、艰难梭菌感染、旅行者腹泻、肠易激综合征、克罗恩病等疾病。此外，布拉迪酵母作为一种饲料添加剂通过了欧洲、北美等认证。在畜禽应用中，布拉迪酵母可降低畜禽料重比、改善生产性能、降低腹泻，同时可以通过促进肠道有益菌的增殖，产生乳酸降低肠道致病菌的含量、调节肠道菌群平衡，促进机体免疫因子的释放和免疫器官的发育，进而增强机体免疫力。作者针对布拉迪酵母生物学功能及其作用机制、在畜禽养殖及人临床上的应用进行综述，以期为其进一步的研究和广泛应用提供参考。

关键词: 布拉迪酵母; 生物学特性; 作用机制; 畜禽养殖

Abstract: Saccharomyces boulardii,a subspecies of Saccharomyces cerevisiae,has high temperature and bile salt resistance.Saccharomyces boulardii reduces intestinal pathogens by altering the surface of pathogens.In addition,the secretion of Saccharomyces boulardii can increase enzyme activity in animals,thereby promoting digestion and absorption of nutrients.Furthermore,the secretion of Saccharomyces boulardii can improve the body's anti-inflammatory effect by interfering with pro-inflammatory factors.Saccharomyces boulardii can prevent and cure diseases such as antibiotic-associated diarrhea,Clostridium difficile infection,traveler's diarrhea,irritable bowel syndrome,crohn's disease and other diseases.Saccharomyces boulardii has been certified in Europe and North America as a feed additive.In livestock and poultry applications,Saccharomyces boulardii can promote the proliferation of intestinal beneficial bacteria,produce lactic acid to reduce the content of intestinal pathogenic bacteria,promote the release of immune factors and the development of immune organs,thus decrease feed and gain ratio,improve the production performance,enhance immunity,reduce diarrhea,and regulate intestinal flora balance.In this paper,the authors reviewed the biological function,mechanism of action and application of Saccharomyces boulardii.It was expected to provide reference for its further research and wide application in the future.

Key words: Saccharomyces boulardii; biological characteristics; mechanism of action; livestock application

中图分类号:

S816.3

卢奇成, 吴妍妍, 张文举. 布拉迪酵母菌的生物学功能、作用机制及其应用[J]. 中国畜牧兽医, 2020, 47(8): 2472-2480.

LU Qicheng, WU Yanyan, ZHANG Wenju. Biological Function,Mechanism of Action and Application of Saccharomyces boulardii[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(8): 2472-2480.

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