[1] Renukaradhya G J, Alekseev K, Jung K, et al.Porcine reproductive and respiratory syndrome virus-induced immunosuppression exacerbates the inflammatory response to porcine respiratory coronavirus in pigs[J].Viral Immunol, 2010, 23(5):457-466. [2] Savard C, Pinilla V, Provost C, et al.In vitro effect of deoxynivalenol (DON) mycotoxin on porcine reproductive and respiratory syndrome virus replication[J].Food Chem Toxicol, 2014, 65:219-226. [3] Corzo C A, Mondaca E, Wayne S, et al.Control and elimination of porcine reproductive and respiratory syndrome virus[J].Virus Res, 2010, 154:185-192. [4] Sterzl J, Rejnek J, Trávnícek J.Impermeability of pig placenta forantibodies[J].Folia Microbiol, 1966, 11:7-10. [5] Karniychuk U U, Saha D, Geldhof M, et al.Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites[J].Microb Pathog, 2011, 51:194-202. [6] Karniychuk U U, Nauwynck H J.Pathogenesis and prevention of placental and transplacental porcine reproductive and respiratory syndrome virus infection[J].Vet Res, 2013, 44:95. [7] Ladinig A, Wilkinson J, Ashley C, et al.Variation in fetal outcome, viral load and ORF5 sequence mutations in a large scale study of phenotypic responses to late gestation exposure to type 2 porcine reproductive and respiratory syndrome virus[J].PLoS One, 2014, 9(4):e96104. [8] Feng D, Nagy J A, Pyne K, et al.Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP[J].Exp Med, 1998, 187(6):903-915. [9] Greenwood J, Howes R, Lightman S.The blood-retinal barrier in experimental autoimmune uveoretinitis.Leukocyte interactions and functional damage[J].Lab Invest, 1994, 70:39-52. [10] Yoon K J, Wu L L, Zimmerman J J, et al.Antibody dependent enhancement (ADE) of porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigs[J].Viral Immunol, 1996, 9:51-63. [11] Tirado S M, Yoon K J.Antibody-dependent enhancement of virus infection and disease[J].Viral Immunol, 2003, 16:69-86. [12] Huttenlocher A, Poznansky M C.Reverse leukocyte migration can be attractive or repulsive[J].Trends Cell Biol, 2008, 18(6):298-306. [13] Karniychuk U U, De Spiegelaere W, Nauwynck H J.Porcine reproductive and respiratory syndrome virus infection is associated with an increased number of Sn-positive and CD8-positive cells in the maternal-fetal interface[J].Virus Res, 2013, 44:285-291. [14] Karniychuk U U, Van Breedam W, Van Roy N, et al.Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection[J].Vet Res, 2012, 43:19-25. [15] Garlow J E, Ka H, Johnson G A, et al.Analysis of osteopontin at the maternal-placental interface in pigs[J].Biol Reprod, 2002, 66:718-725. [16] Rashev P, Georgieva R, Rees D.Expression of alpha5beta1 integrin and fibronectin during early pregnancy in pigs[J].Folia Biol (Praha), 2005, 51:121-125. [17] Rowland R R.The interaction between PRRSV and the late gestation pig fetus[J].Virus Res, 2010, 154:114-122. [18] Olanratmanee E O, Wangnaitham S, Thanawongnuwech R, et al.Prevalence of porcine reproductive and respiratory syndrome virus (PRRSV) antigen-positive uterine tissues in gilts culled due to reproductive disturbance in Thailand[J].Trop Anim Health Prod, 2011, 43(2):451-458. [19] Stockhofe-Zurwieden N, Navarro Camarro J A, Grosse-Beilage E, et al.Uterine and placental alterations in pregnant sows associatedwith the porcine epidemic abortion and respiratory syndrome (PEARS)[J].Zentralbl Veterinarmed B, 1993, 40:261-271. [20] Lager K M, Halbur P G.Gross and microscopic lesions in porcine fetuses infected with porcine reproductive and respiratory syndrome virus[J].Vet Diagn Invest, 1996, 8:275-282. [21] Prieto C, Sánchez R, Martín-Rillo S, et al.Exposure of gilts in early gestation to porcine reproductive and respiratory syndrome virus[J].Vet Rec, 1996, 138:536-539. [22] Mateusen B, Van Soom A, Maes D G, et al.Receptor-determined susceptibility of preimplantation embryos to pseudorabies virus and porcine reproductive and respiratory syndrome virus[J].Biol Reprod, 2007, 76:415-423. [23] Christianson W T, Collins J E, Benfield D A, et al.Experimental reproduction of swine infertility and respiratory syndrome in pregnant sows[J].Am J Vet Res, 1992, 53:485-488. [24] Kranker S, Nielsen J, Bille-Hansen V, et al.Experimental inoculation of swine at various stages of gestation with a Danish isolate of porcine reproductive and respiratory syndrome virus (PRRSV)[J].Vet Microbiol, 1998, 61:21-31. [25] Mengeling W L, Lager K M, Vorwald A C.Temporal characterization of transplacental infection of porcine fetuses with porcine reproductive and respiratory syndrome virus[J].Am J Vet Res, 1994, 55:1391-1398. [26] Prieto C, García C, Simarro I, et al.Temporal localization of porcine reproductive and respiratory syndrome virus in reproductive tissues of experimentally infected boars[J].Theriogenology, 2003, 60(8):1505-1514. [27] Sur J H, Doster A R, Christian J S, et al.Porcine reproductive and respiratory syndrome virus replicates in testicular germ cells, alters spermatogenesis and induces germ cell death by apoptosis[J].J Virol, 1997, 71(12):9170-9179. [28] Christopher-Hennings J, Nelson E A, Nelson J K, et al.Identification of porcine reproductive and respiratory syndrome virus in semen and tissues from vasectomized and nonvasectomized boars[J].Vet Pathol, 1998, 35(4):260-267. [29] Christopher-Hennings J, Nelson E A, Hines R J, et al.Persistence of porcine reproductive and respiratory syndrome virus in serum and semen of adult boars[J].Vet Diagn Invest, 1995, 7(4):456-464. [30] Christopher-Hennings J, Holler L D, Benfield D A, et al.Detection and duration of porcine reproductive and respiratory syndrome virus in semen, serum, peripheral blood mononuclear cells, and tissues from Yorkshire, Hampshire, and Landrace boars[J].Vet Diagn Invest, 2001, 13:133-142. [31] Bøtner A, Strandbygaard B, Sorensen K J, et al.Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine[J].Vet Rec, 1997, 141:497-499. [32] Park B K, Yoon I J, Joo H S.Pathogenesis of plaque variants of porcine reproductive and respiratory syndrome virus in pregnant sows[J].Am J Vet Res, 1996, 57:320-323. [33] Karniychuk U U, Geldhof M, Vanhee M, et al.Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate[J].BMC Vet Res, 2010, 6:30-39. [34] 黄勤锋.猪繁殖与呼吸综合征病毒的感染性克隆及其复制子载体的研究[D].武汉:华中农业大学, 2009. [35] Cheon D S, Chae C.Distribution of porcine reproductive and respiratory syndrome virus in stillborn and liveborn piglets from experimentally infected sows[J].J Comp Pathol, 2001, 124:231-237. [36] Lunney J K, Benfield D A, Rowland R R.Porcine reproductive and respiratory syndrome virus:An update on an emerging and re-emerging viral disease of swine[J].Virus Res, 2010, 154:1-6. [37] Prieto C, Castro J M.Porcine reproductive and respiratory syndrome virus infection in the boar:A review[J].Theriogenology, 2005, 63:1-16. [38] 姚敬明, 孟 帆, 吴 忻, 等.猪繁殖与呼吸综合征母源抗体和免疫抗体的消长规律研究[J].中国畜牧兽医, 2010, 37(4):205-208. [39] Kang I, Ha Y, Kim D, et al.Localization of porcine reproductive and respiratory syndrome virus in mammary glands of experimentally infected sows[J].Res Vet Sci, 2010, 88(2):304-310. [40] Rowland R R, Lawson S, Rossow K, et al.Lymphoid tissue tropism of porcine reproductive and respiratory syndrome virus replication during persistent infection of pigs originally exposed to virus in utero[J].Vet Microbiology, 2003, 96(3):219-235. [41] Done S H, Paton D J.Porcine reproductive and respiratory syndrome:Clinical disease, pathology and immunosuppression[J].Vet Rec, 1995, 136:32-35. [42] Wills R W, Doster A R, Galeota J A, et al.Duration of infection and proportion of pigs persistently infected with porcine reproductive and respiratory syndrome virus[J].Clin Microbiol, 2003, 41:58-62. [43] Riber U, Nielsen J, Lind P.In utero infection with PRRS virus modulates cellular functions of blood monocytes and alveolar lung macrophages in piglets[J].Vet Immunol Immunopathol, 2004, 99(3-4):169-177. [44] Feng W, Laster S M, Tompkins M, et al.In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis typeⅡ[J].Journal of Virology, 2001, 75(10):4889-4895. [45] Brockmeier S L, Palmer M V, Bolin S R, et al.Effects of intranasal inoculation with Bordetella bronchiseptica, porcine reproductive and respiratory syndrome virus, or a combination of both organisms on subsequent infection with Pasteurella multocida in pigs[J].Am J Vet Res, 2001, 62(4):521-526. [46] Sinha A, Shen H G, Schalk S, et al.Porcine reproductive and respiratory syndrome virus (PRRSV) influences infection dynamics of porcine circovirus type 2 (PCV2) subtypes PCV2a and PCV2b by prolonging PCV2 viremia and shedding[J].Vet Microbiol, 2011, 152(3-4):235-246. [47] Prieto C, Suárez P, Simarro I, et al.Transplacental infection following exposure of gilts to porcine reproductive and respiratory syndrome virus at the onset of gestation[J].Vet Microbiol, 1997, 57:301-311. [48] Sun X Z, Wertz N, Lager K L, et al.Antibody repertoire development in fetal and neonatal piglets.ⅩⅩⅢ:Fetal piglets infected with a vaccine strain of PRRS virus display the same immune dysregulation seen in isolator piglets[J].Vaccine, 2012, 30(24):3646-3652. [49] Stuart A D, Brown T D K, Mockett A P A.Tywalosin, a macrolide antibiotic, inhibits the in-vitro replication of European and American porcine reproductive and respiratory syndrome virus (PRRS) viruses[J].The Pig Journal, 2008, 61:42-48. |