›› 2012, Vol. 39 ›› Issue (2): 159-163.

• 疾病防治 • Previous Articles     Next Articles

Research Approach of Molecular Biology of Rabies Virus

JU Mei-fang, YIN Xiang-ping, JIAO Wen-qiang, LIU Ji-xing   

  1. State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Grazing Animal Disease of the Ministry of Agriculture,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046,China
  • Received:2011-08-21 Revised:1900-01-01 Online:2012-02-20 Published:2012-02-20

Abstract: Rabies is a zoonotic diseases occured in central nervous system. All warm-blooded animals can be infected. At present, there are no effective medicine to cure rabies, once infected the fatality rate is almost 100%. The genome of rabies virus encode 5 structural proteins. All the structural proteins play an important role in virus life cycle, including pathogenesis, transcription and replication of the virus. The antigenicity and gene sequence of the structural proteins can be used for the virus classification. The functions of the 5 structural proteins were expounded in this paper.

Key words: rabies; rabies virus; structural proteins

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