过氧化物酶体增殖物激活受体α在猪肝脏组织中发育性表达研究

Abstract

Abstract: To investigate the developmental expression patterns of PPARα gene in liver of different lard type pigs in this study,we detected the PPARα expression changes of mRNA at the ages of 0,1,2,3,4,5 and 6 months in the livers of Mashen pigs and Large White pigs by qRT-PCR. This results showed that the expression of PPARα mRNA in liver exhibited specific developmental changes and different patterns between the two pig breed. At the same time,developmental expression patterns of PPARα mRNA in Large White pigs established the higher in adjacent periods,the highest in 0 month,but the lowest in 3 month,which showed highly significant between the two monthes (P<0.01),while the higher in the early period and the lower in the later period for Mashen pigs,the expression level in 0 and 1 months was significantly higher than that of other months (P<0.01). The results revealed that PPARα was a regulatory factor involved in the liver lipid metabolism,which provided the theory data for the regulatory mechanism of fat deposition in pigs.

Key words: pig; PPARα gene; mRNA; developmental expression

CLC Number:

Q786

XU Kai, WANG Xiao-jing, LIU Hong, GUO Xiao-hong, GAO Peng-fei, CAO Guo-qing, LI Bu-gao. Study on Developmental Expression of PPARα mRNA in Liver Tissues of Pig[J]. , 2014, 41(10): 178-182.

References

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Study on Developmental Expression of PPARα mRNA in Liver Tissues of Pig

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