酵母CUP1基因的结构及其蛋白质鳌合金属离子功能的研究进展

Abstract

Abstract: Yeast (Saccharomyces cerevisiae) CUP1 encodes a cysteine-rich protein with 61 amino acids in length and 6165 u in molecular weight. Yeast CUP1 is a copper metallothionein responsible for resistance to copper. Yeast is induced by copper, and the CUP1 expression is greatly enhanced at the mRNA lever driven by the strong combination of the CUP1 promoter and the factor ACE1.This article summarizes the progress on the yeast CUP1 gene. It mainly describes the structure, the role of binding metal-ion, and the analysis on the promoter of CUP1 gene. Also, it describes the application of the CUP1 gene, especially for the CUP1 promoter, for the transgenic organisms. It plays an essential role on the further research of the physiological mechanism of CUP1 gene, and provides theoretical assistance for the transgenic organisms, especially for the transgenic animals and plants.

Key words: yeast; CUP1 gene; binding; promoter; transgene

CLC Number:

XIE Xiao-xian, WANG Qi-shan, CHEN Zhen-liang, MA Yu-fang, PAN Yu-chun. Research Progress on the Structure and the Function on Binding Metal-ion of Yeast CUP1 Gene[J]. , 2013, 40(3): 62-67.

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Research Progress on the Structure and the Function on Binding Metal-ion of Yeast CUP1 Gene

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