Abstract: This experiment aims to investigate Chinese medicinal compound polysaccharide’s (CMCP) influence on mice blood index with different components and different degrees of purity. In our experiment firstly we select cyclophosphamide to build mice immunity-inhibition model and then we respectively gavage CMCP with different components and different degrees of purity, compound total polysaccharide and compound water decoction into mice to measure their effects on mice’s peripheral hemogram. The result shows that polysaccharide A2, purity polysaccharide B2, compound total polysaccharide and compound water decoction can significantly increase the number of erythrocytes, the number of leukocytes, neutrophilic granulocyte’s percentage in leukocyte classification number and the percentage of lymphocytes in mice. The result also shows a very significant difference from the model group (P<0.01). Therefore it can be seen that polysaccharide A2, purity polysaccharide B2, compound total polysaccharide and compound water decoction can improve reduced peripheral hemogram in mice blood index, which is caused by cyclophosphamide, to regulate immune imbalance.

Key words: polysaccharide with different components; polysaccharide with different degrees of purity; mice; immunity-inhibition model; blood index