干扰素制剂冻干技术研究进展

Abstract

Abstract: Interferon products, with the broad-spectrum antiviral and immunomodulatory activity, have broad application prospects in the field of medicine and clinical veterinary medicine. In the actual practice, liquid dosage form of interferon preparations has the problems of poor thermal stability, difficult long-term preservation, long-distance transportation, et al. However, the shelf life and stability of the lyophilized interferon preparations could be increased. In this paper, the principle of freeze-drying technology, screening of lyoprotectant and freeze-dried process for interferon products are reviewed.

Key words: interferon; lyophilization; lyoprotectant; freeze-dried process

CLC Number:

S859.79⁺7

ZHANG Dai-bao, WU Zhi-ming, ZHAO Ming-jun, ZHANG Lin-hai, YAN Ruo-qian. Research Progress on Interferon Freeze-drying Technology[J]. , 2012, 39(10): 57-60.

References

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