自噬调控猪脂肪生成的研究进展

doi:10.16431/j.cnki.1671-7236.2024.12.020

Abstract

Abstract: Adipose tissue is an energy storage station in the animal organism and an important endocrine organ.Obesity caused by excessive fat deposition brings about a series of metabolic diseases,such as fatty liver,cardiovascular disease and insulin resistance.Similarly,porcine adipogenesis influences traits such as disease resistance,reproductive performance,meat quality and productivity,which affect the economic efficiency of hog production.Mature adipocytes are obtained by differentiation of mesenchymal stem cells,a process in which many signaling pathways and transcription factors are involved via preadipocytes.Autophagy is usually the most important means of catabolizing redundant components of the organism and is involved in the maintenance of homeostasis.There is a close link between autophagy and adipogenesis,active adipogenesis is accompanied by elevated levels of autophagy,and impaired autophagy is accompanied by suppressed adipogenesis.There are many related transcription factors and signaling pathways that regulate porcine adipogenesis during autophagic activities,and many transcription factors are involved in the process of porcine adipogenesis.By summarizing the newly reported transcription factors and signaling pathways related to autophagy regulation of adipogenesis,the author elaborates the research progress on autophagy involved in the regulation of porcine adipogenesis,which provides a new idea and target point for the regulation of porcine nutrition and meat quality breeding.

Key words: pigs; autophagy; adipogenesis; transcription factor; regulation

CLC Number:

S852.23

HONG Chun, ZHU Xiangxing, LI Xinming, HUANG Qiuyan, LIU Wenhua, DU Zongliang, TANG Dongsheng, WANG Sutian. Progress on Autophagy Regulation of Porcine Adipogenesis[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(12): 5325-5334.

References

[1] SUI G, JIA L, SONG N, et al.Aberrant expression of HDL-bound microRNA induced by a high-fat diet in a pig model:Implications in the pathogenesis of dyslipidaemia[J].BMC Cardiovascular Disorders, 2021, 21(1):280.
[2] PIORKOWSKA K, ZUKOWSKI K, ROPKA-MOLIK K, et al.Variations in fibrinogen-like 1(FGL1) gene locus as a genetic marker related to fat deposition based on pig model and liver RNA-Seq data[J].Genes, 2022, 13(8):1419.
[3] KOCIUCKA B, JACKOWIAK H, KAMYCZEK M, et al.The relationship between adipocyte size and the transcript levels of SNAP23, BSCL2 and COPA genes in pigs[J].Meat Science, 2016, 121:12-18.
[4] OTTO T C, LANE M D.Adipose development:From stem cell to adipocyte[J].Critical Reviews in Biochemistry and Molecular Biology, 2005, 40(4):229-242.
[5] KHAN F, KHAN H, KHAN A, et al.Autophagy in adipogenesis:Molecular mechanisms and regulation by bioactive compounds[J].Biomedicine & Pharmacotherapy, 2022, 155:113715.
[6] ANDERSON D B, KAUFFMAN R G.Cellular and enzymatic changes in porcine adipose tissue during growth[J].Journal of Lipid Research, 1973, 14(2):160-168.
[7] 徐宜兰, 方启晨.棕色脂肪和白色脂肪棕色化的调控研究新进展[J].医学研究杂志, 2017, 46(2):3-6.XU Y L, FANG Q C.New progress in the study of regulation of brown fat and white fat browning[J].Journal of Medical Research, 2017, 46(2):3-6.(in Chinese)
[8] ROSEN E D, SPIEGELMAN B M.What we talk about when we talk about fat[J]. Cell, 2014, 156(1-2):20-44.
[9] HAUNER H.Secretory factors from human adipose tissue and their functional role[J].The Proceedings of the Nutrition Society, 2005, 64(2):163-169.
[10] WEISBERG S P, MCCANN D, DESAI M, et al.Obesity is associated with macrophage accumulation in adipose tissue[J].The Journal of Clinical Investigation, 2003, 112(12):1796-1808.
[11] 陈绍红, 陈育峰, 刘铀, 等.猪前脂肪细胞增殖与分化的初步观察[J].西南师范大学学报(自然科学版), 2010, 35(3):208-211.CHEN S H, CHEN Y F, LIU U, et al.Obsrevation of porcine preadipocyte proliferation and differentiation in vivo[J]. Journal of Southwest Normal University (Natural Science Edition), 2010, 35(3):208-211.(in Chinese)
[12] MOTA D S P, RICHARD A J, HANG H, et al.Transcriptional regulation of adipogenesis[J].Comprehensive Physiology, 2017, 7(2):635-674.
[13] WANG Z, LI Y, WU L, et al.Rosiglitazone-induced PPARgamma activation promotes intramuscular adipocyte adipogenesis of pig[J].Animal Biotechnology, 2023, 34(8):3708-3717.
[14] CHEN J, DODSON M V, JIANG Z.Cellular and molecular comparison of redifferentiation of intramuscular- and visceral- adipocyte derived progeny cells[J].International Journal of Biological Sciences, 2010, 6(1):80-88.
[15] 巩建飞, 刘欣, 孙金海, 等.猪脂肪细胞分化及调控研究进展[J].农业生物技术学报, 2020, 28(2):325-332.GONG J F, LIU X, SUN J H, et al.Advances in the differentiation and regulation of porcine (Sus scrofa) adipocytes [J].Journal of Agricultural Biotechnology, 2020, 28(2):325-332.(in Chinese)
[16] JAKAB J, MISKIC B, MIKSIC S, et al.Adipogenesis as a potential anti-obesity target:A review of pharmacological treatment and natural products[J].Diabetes, Metabolic Syndrome and Obesity:Targets and Therapy, 2021, 14:67-83.
[17] YAN H, LI Q, LI M, et al.Ajuba functions as a co-activator of C/EBPbeta to induce expression of PPARgamma and C/EBPalpha during adipogenesis[J].Molecular and Cellular Endocrinology, 2022, 539:111485.
[18] YUCE K, OZKAN A I.The Krüppel-like factor (KLF) family, diseases, and physiological events[J].Gene, 2024, 895:148027.
[19] DU J, XU Y, ZHANG P, et al.microRNA-125a-5p affects adipocytes proliferation, differentiation and fatty acid composition of porcine intramuscular fat[J].International Journal of Molecular Sciences, 2018, 19(2):501.
[20] ZHAO X, CHEN S, TAN Z, et al.Transcriptome analysis of landrace pig subcutaneous preadipocytes during adipogenic differentiation[J].Genes, 2019, 10(7):552.
[21] DAHLMAN I, ARNER P.Genetics of adipose tissue biology[J].Progress in Molecular Biology and Translational Science, 2010, 94:39-74.
[22] ZHANG J, MENG S, WANG H, et al.Comparison of growth performance, carcass properties, fatty acid profile, and genes involved in fat metabolism in Nanyang and Landrace pigs[J]. Genes, 2024, 15(2):186.
[23] CIRERA S, JENSEN M S, ELBROND V S, et al.Expression studies of six human obesity-related genes in seven tissues from divergent pig breeds[J].Animal Genetics, 2014, 45(1):59-66.
[24] ZHANG S, CUI Y, GAO X, et al.Resveratrol inhibits the formation and accumulation of lipid droplets through AdipoQ signal pathway and lipid metabolism lncRNAs[J].The Journal of Nutritional Biochemistry, 2023, 117:109351.
[25] AMBELE M A, DHANRAJ P, GILES R, et al.Adipogenesis:A complex interplay of multiple molecular determinants and pathways[J].International Journal of Molecular Sciences, 2020, 21(12):4283.
[26] 罗肖.Wnt/β-catenin信号通路在猪脂肪组织发育过程中的调控作用[D].杨凌：西北农林科技大学, 2008.LUO X.Regulation of Wnt/β-catenin signaling pathway during porcine adipose tissue development [D].Yangling:Northwest A&F University, 2008.(in Chinese)
[27] 李银, 韦洋洋, 蒋钦杨, 等.动物肌内脂肪沉积的影响因素及其分子机制[J].动物营养学报, 2024, 36(3):1502-1514.LI Y, WEI Y Y, JIANG Q Y, et al.Affecting factors of intramuscular fat deposition in animals and their molecular mechanisms[J].Chinese Journal of Animal Nutrition, 2024, 36(3):1502-1514.(in Chinese)
[28] ZHANG Y, ZENG X, JIN S.Autophagy in adipose tissue biology[J].Pharmacological Research, 2012, 66(6):505-512.
[29] LI W W, LI J, BAO J K.Microautophagy:Lesser-known self-eating[J].Cellular and Molecular Life Sciences, 2012, 69(7):1125-1136.
[30] CUERVO A M, WONG E.Chaperone-mediated autophagy:Roles in disease and aging[J]. Cell Research, 2014, 24(1):92-104.
[31] YIN L, DAI Y, CUI Z, et al.The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2alpha/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity[J].Toxicology and Applied Pharmacology, 2017, 314:98-108.
[32] KAWABATA T, YOSHIMORI T.Beyond starvation:An update on the autophagic machinery and its functions[J].Journal of Molecular and Cellular Cardiology, 2016, 95:2-10.
[33] HARA T, TAKAMURA A, KISHI C, et al.FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells[J].The Journal of Cell Biology, 2008, 181(3):497-510.
[34] ZHOU C, WU Z, DU W, et al.Recycling of autophagosomal components from autolysosomes by the recycler complex[J].Nature Cell Biology, 2022, 24(4):497-512.
[35] MIZUSHIMA N, KUMA A, KOBAYASHI Y, et al.Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate[J].Journal of Cell Science, 2003, 116(Pt 9):1679-1688.
[36] 马海龙, 刘万林.细胞自噬分子机制研究进展[J].内蒙古医科大学学报, 2015, 37(S1):87-92.MA H L, LIU W L.The research progression of autophagy molecular mechanisms [J].Journal of Inner Mongolia Medical University, 2015, 37(S1):87-92.(in Chinese)
[37] BURGOYNE J R.Oxidative stress impairs autophagy through oxidation of ATG3 and ATG7[J].Autophagy, 2018, 14(6):1092-1093.
[38] ZHENG Z, ZHAO M, SHAN H, et al.Noncanonical autophagy is a new strategy to inhibit HSV-1 through STING1 activation[J].Autophagy, 2023, 19(12):3096-3112.
[39] ISHIHARA N, HAMASAKI M, YOKOTA S, et al.Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion[J].Molecular Biology of the Cell, 2001, 12(11):3690-3702.
[40] KING K E, LOSIER T T, RUSSELL R C.Regulation of autophagy enzymes by nutrient signaling[J].Trends in Biochemical Sciences, 2021, 46(8):687-700.
[41] 邓亦宁, 张云科, 焦晓宇, 等.细菌感染诱发细胞自噬的研究进展[J].热带生物学报, 2023, 14(3):279-287.DENG Y M, ZHANG Y K, JIAO X Y, et al.Advances in autophagy induced by bacterial infection[J]. Journal of Tropical Biology, 2023, 14(3):279-287.(in Chinese)
[42] 王改丽, 郝良玉, 郭衍冰, 等.转录因子EB调控相关疾病研究进展[J].动物医学进展, 2022, 43(9):95-99.WANG G L, HAO L Y, GUO Y B, et al.Progress on transcription factor EB in regulation of related diseases[J].Progress in Veterinary Medicine, 2022, 43(9):95-99.(in Chinese)
[43] BAERGA R, ZHANG Y, CHEN P H, et al.Targeted deletion of autophagy-related 5(Atg5) impairs adipogenesis in a cellular model and in mice[J].Autophagy, 2009, 5(8):1118-1130.
[44] HEINITZ S, GEBHARDT C, PIAGGI P, et al.Atg7 knockdown reduces chemerin secretion in murine adipocytes[J].The Journal of Clinical Endocrinology and Metabolism, 2019, 104(11):5715-5728.
[45] ZHANG Y, GOLDMAN S, BAERGA R, et al.Adipose-specific deletion of autophagy-related gene 7(Atg7) in mice reveals a role in adipogenesis[J].Proceedings of the National Academy of Sciences of the United States of America, 2009, 106(47):19860-19865.
[46] WANG X, WU R, LIU Y, et al.m(⁶) A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7[J].Autophagy, 2020, 16(7):1221-1235.
[47] 吴睿帆.FTO对猪前体脂肪细胞成脂分化的影响及调控机制研究[D].杭州：浙江大学, 2020.WU R F.Effects and regulatory mechanisms of FTO on adipogenesis of porcine preadipocytes[D].Hangzhou:Zhejiang University, 2022.(in Chinese)
[48] LING M, QIAN H, GUO H.Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy[J].In Vitro Cellular & Developmental Biology.Animal, 2024, 60(3):258-265.
[49] RO S H, JUNG C H, HAHN W S, et al.Distinct functions of ULK1 and ULK2 in the regulation of lipid metabolism in adipocytes[J].Autophagy, 2013, 9(12):2103-2114.
[50] JIANG W J, LEE S H, HEO G, et al.Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos[J].Frontiers in Cell and Developmental Biology, 2023, 11:1238546.
[51] WU R, FENG S, LI F, et al.Transcriptional and post-transcriptional control of autophagy and adipogenesis by YBX1[J].Cell Death & Disease, 2023, 14(1):29.
[52] WU R, CAO S, LI F, et al.RNA-binding protein YBX1 promotes brown adipogenesis and thermogenesis via PINK1/PRKN-mediated mitophagy[J].Federation of American Societies for Experimental Biology, 2022, 36(3):e22219.
[53] DARLINGTON G J, ROSS S E, MACDOUGALD O A.The role of C/EBP genes in adipocyte differentiation[J].The Journal of Biological Chemistry, 1998, 273(46):30057-30060.
[54] PARK B H, QIANG L, FARMER S R.Phosphorylation of C/EBPbeta at a consensus extracellular signal-regulated kinase/glycogen synthase kinase 3 site is required for the induction of adiponectin gene expression during the differentiation of mouse fibroblasts into adipocytes[J].Molecular and Cellular Biology, 2004, 24(19):8671-8680.
[55] TANG Q Q, GRONBORG M, HUANG H, et al.Sequential phosphorylation of CCAAT enhancer-binding protein beta by MAPK and glycogen synthase kinase 3beta is required for adipogenesis[J].Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(28):9766-9771.
[56] LI X, KIM J W, GRONBORG M, et al.Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation[J].Proceedings of the National Academy of Sciences of the United States of America, 2007, 104(28):11597-11602.
[57] KIM J W, TANG Q Q, LI X, et al.Effect of phosphorylation and S-S bond-induced dimerization on DNA binding and transcriptional activation by C/EBPbeta[J]. Proceedings of the National Academy of Sciences of the United States of America, 2007, 104(6):1800-1804.
[58] TANG Q Q, LANE M D.Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation[J].Genes & Development, 1999, 13(17):2231-2241.
[59] 熊燕.C/EBPβ和FoxO1通过反馈环和蛋白互作调控猪前体脂肪细胞分化[D].杨凌：西北农林科技大学, 2013.XIONG Y.C/EBPβ and FoxO1 regulate porcine preadipocyte differentiation through feedback loop and protein interaction[D].Yangling:Northwest A&F University, 2013.(in Chinese)
[60] ZHANG Y, ZHANG J, WANG C, et al.The super-enhancer repertoire in porcine liver[J].Journal of Animal Science, 2023, 101:skad056.
[61] LI X, TANG J, XU J, et al.The inflammation-related gene S100A12 is positively regulated by C/EBPbeta and AP-1 in pigs[J].International Journal of Molecular Sciences, 2014, 15(8):13802-13816.
[62] XIA F, CHEN H, LIU Y, et al.Development of genomic phenotype and immunophenotype of acute respiratory distress syndrome using autophagy and metabolism-related genes[J].Frontiers in Immunology, 2023, 14:1209959.
[63] TAO Z, SHI L, PARKE J, et al.Sirt1 coordinates with ERalpha to regulate autophagy and adiposity[J].Cell Death Discovery, 2021, 7(1):53.
[64] CUI S, SONI C B, XIE J, et al.miR-30a-5p accelerates adipogenesis by negatively regulating Sirtuin 1[J].International Journal of Clinical and Experimental Pathology, 2018, 11(11):5203-5212.
[65] BAI L, PANG W J, YANG Y J, et al.Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes[J].Molecular and Cellular Biochemistry, 2008, 307(1-2):129-140.
[66] PANG W, WANG Y, WEI N, et al.Sirt1 inhibits Akt2-mediated porcine adipogenesis potentially by direct protein-protein interaction[J].PLoS One, 2013, 8(8):e71576.
[67] PAN S, CUI Y, FU Z, et al.microRNA-128 is involved in dexamethasone-induced lipid accumulation via repressing SIRT1 expression in cultured pig preadipocytes[J].The Journal of Steroid Biochemistry and Molecular Biology, 2019, 186:185-195.
[68] PENG J, ZHOU Y, DENG Z, et al.miR-221 negatively regulates inflammation and insulin sensitivity in white adipose tissue by repression of sirtuin-1(SIRT1)[J].Journal of Cellular Biochemistry, 2018, 119(8):6418-6428.
[69] LI Y, MA Z, JIANG S, et al.A global perspective on FOXO1 in lipid metabolism and lipid-related diseases[J].Progress in Lipid Research, 2017, 66:42-49.
[70] FULLGRABE J, KLIONSKY D J, JOSEPH B.The return of the nucleus:Transcriptional and epigenetic control of autophagy[J].Nature Reviews.Molecular Cell Biology, 2014, 15(1):65-74.
[71] LIU L, ZHENG L D, ZOU P, et al.FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes[J]. Cell Cycle, 2016, 15(15):2033-2041.
[72] YAN X, WEIJUN P, NING W, et al.Knockdown of both FoxO1 and C/EBPbeta promotes adipogenesis in porcine preadipocytes through feedback regulation[J].Cell Biology International, 2013, 37(9):905-916.
[73] YAN X, WEIJUN P, NING W, et al.miR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1[J].Acta Biochimica et Biophysica Sinica, 2014, 46(7):565-571.
[74] JIAO D, YANG Z, WANG L, et al.Endogenous leptin promotes autophagy in EBSS-induced PFCs[J].Animal Cells and Systems, 2019, 23(5):318-325.
[75] GAO P, WANG H, LIU J, et al.miR-128 regulated the proliferation and autophagy in porcine adipose-derived stem cells through targeting the JNK signaling pathway[J].Journal of Receptor and Signal Transduction Research, 2021, 41(2):196-201.
[76] SUN Y, CAI R, WANG Y, et al.A newly identified lncRNA lncIMF4 controls adipogenesis of porcine intramuscular preadipocyte through attenuating autophagy to inhibit lipolysis[J].Animals：An Open Access Journal from MDPI, 2020, 10(6):962.
[77] WANG J, LIU J Y, SHAO K Y, et al.Porcine reproductive and respiratory syndrome virus activates lipophagy to facilitate viral replication through downregulation of NDRG1 expression[J].Journal of Virology, 2019, 93(17):e00526-19.
[78] 徐永健, 冯贤辀, 蒙利洁, 等.鲜味受体TAS1R1/TAS1R3对从江香猪肌内前体脂肪细胞自噬及脂质代谢的调控研究[J].中国畜牧杂志, 2021, 57(10):100-105.XU Y J, FENG X L, MONG L J, et al.Regulation of autophagy and lipid metabolism in intramuscular precursor adipocytes of Congjiang scented pig by fresh flavor receptor TAS1R1/TAS1R3[J]. Chinese Journal of Animal Science, 2021, 57(10):100-105.(in Chinese)

Progress on Autophagy Regulation of Porcine Adipogenesis

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