Abstract: One hundred and twenty Kunming mice were randomly divided into four groups(Ⅰ,Ⅱ,Ⅲ,Ⅳ) with 30 mice per group(half female and half male). Ⅰgroup was conventional feeding as a control group, Ⅱ,Ⅲ,Ⅳgroups were respectively added to different proportion of compound traditional Chinese medicine in the feed with 0.75%, 1.00% and 1.50% of compound Chinese medicine. Results showed that thymus index and spleen index of mice in Ⅲ, Ⅳgroups were significant increase(P<0.05 or P<0.01) in the third week, compared to control group. When serum biochemical index of mice was determined in the first and the third week, total protein (TP) and albumin (ALB) in Ⅱ,Ⅲ and Ⅳgroups, cholesterol (CHO) and triglyceride (TG) in Ⅲ and Ⅳ groups, all increased significantly (P<0.05 or P<0.01). Meanwhile, MID and LYM of mice in Ⅲ and Ⅳ groups also increased (P<0.05). In conclusion, the immune organs development of mice can be promoted which were fed with Chinese herbal medicine superfine powder.

Key words: Chinese herbal ultra-fine powder; thymus index; spleen index; serum biochemical index; blood routine examination; mice