Previous Articles     Next Articles

Effect of Astragalus Polysaccharin on Growth Performance,Intestinal Microflora and Immune Function of Immunosuppression Broilers

SUN Bo1,CHEN Jing1,WU Juan2,LIU Jiang3,CHEN Hong-lan1,LI Wei-ping1   

  1. 1.Department of Agricultural Engineering,Bijie Vocational and Technical College,Bijie 551700,China;2.Bijie Institute for Food and Drug Control,Bijie 551700,China;3.Bijie Animal Disease Prevention and Control Center,Bijie 551700,China
  • Received:2014-03-28 Online:2014-08-20 Published:2014-08-22

Abstract: The aim of this study was to explore the effect of different levels of Astragalus polysaccharin on growth performance,intestinal microflora and immune function of immunosuppression broilers.A total of 180 fast large yellow feather chickens with similar weight were randomly divided into 4 groups,with 3 replicates of 15 chicks in each replicate,group Ⅰ was fed with basal diet,free drinking water,groupsⅡ,Ⅲ,Ⅳ were add 200 mg/L water soluble florfenicol in the drinking water,medication for 6 days,then group Ⅱ was fed a basal diet,groups Ⅲ,Ⅳ were fed with basal diet supplemented with 500 and 1000 mg/kg Astragalus polysaccharin,respectively.The pre-trial period lasted for 7 days,and the experiment lasted for 35 days.The results showed that compared with group Ⅱ,groups Ⅲ and Ⅳ was significantly improved the growth performance of immunosuppression broilers (P<0.05),enhanced the number of beneficial bacteria (Lactobacillus and Bifidobacterium) in the gastrointestinal tract of immunosuppression broilers (P<0.05),reduced the number of harmful bacteria (Escherichia coli and Salmonella) in the gastrointestinal tract of immunosuppression broilers (P<0.05),improved the immune organs index and Newcastle disease antibody titer of immunosuppression broilers (P<0.05),decreased the serum contents of IL-10 and IFN-γ of immunosuppression broilers (P<0.05).In conclusion,adding 500 and 1000 mg/kg Astragalus polysaccharin in diet could eliminate immunosuppression effect of florfenicol test,improve the growth performance,adjust the intestinal micro ecological balance and ennhance the immune function of broilers.

Key words: Astragalus polysaccharin; broiler; florfenicol; immunosuppression; growth performance; intestinal microflora; immune function