树突状细胞在诱导免疫耐受中作用机制的研究进展

Abstract

Abstract: The dendritic cells played a central role in antigen recognition,offer,induced proliferation of T cells and antigen-specific immune response.In recent years, it was found that the cells could also induce immune tolerance and this role was a hotspot in immune tolerance research.This article elaborated the research satus from two aspects, the central and peripheral tolerance. The mechanisms were summarized from five aspects,the regulatory T cells, the surface of the inhibitory molecule,mature state, the microenvironment and intracellular signal transduction. The overview would provide relevant informations for the research of the dendritic cell tolerance.

Key words: dendritic cell; immune tolerance; mechanism of action

CLC Number:

R392.9

LI Song, HE Hao, SONG Wen-gang. Research Progress on Effects and Mechanisms of Dendritic Cells in the Induction of Immune Tolerance[J]. , 2013, 40(6): 100-103.

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Research Progress on Effects and Mechanisms of Dendritic Cells in the Induction of Immune Tolerance

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