蛋白质组学技术在病毒及其感染机制研究中的应用

Abstract

Abstract: In the field of virology, the proteomics technologies wildly is used,such as two-dimensional difference electrophoresis, mass spectrometry, Stable-isotope labeling by amino acids in cell culture, and so on. These mainly methods are applied to analyse the dynamic changes of the components, expression level and post-translational modification of proteins from the whole level, then to explore the proteins function and the interact and correlate with them. These will contribute to research the mechanism of viruses infecting the hosts and the interactions, and promote development of diagnosis and treatment of the diseases caused by viruses. In this study, the applications of proteomics technologies in the research of virus and its infection mechanism were discussed and the prospect in virology study would also be forecasted.

Key words: proteomic; virus; infection mechanism; application

CLC Number:

Q816

SUN Cheng-you, LI Juan, LIU Yu-tian, LI Yu-bao, CHI Tian-ying, SONG Fang, YU Xiao-jing, WANG Zhi-liang. The Application of Proteomics Technologies in the Research of Virus and its Infection Mechanism[J]. , 2013, (5): 75-79.

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The Application of Proteomics Technologies in the Research of Virus and its Infection Mechanism

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