›› 2012, Vol. 39 ›› Issue (7): 151-154.

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The Research of TAT-SOD Protecting Nerve Cell from Apoptosis

LI He, ZHENG Shi-min   

  1. College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China
  • Received:2012-01-11 Online:2012-07-20 Published:2012-07-16

Abstract: Normally, the body exists a set of relatively complete oxidation-antioxidant balance system. In the pathological conditions, this system imbalances to oxidation direction which can cause a series of damage to the body and produce the large amount of free radicals. TAT can mediate SOD through hemato encephalic barrier into the cells even mitochondria, playing the oxidation resistance and protection, especially to nerve cells. At present, the mechanism of TAT mediates allogenic material into cells has different viewpoints and the viewpoints are not clear and persuasive. So it is very important to summarize the research progress of TAT in recent years which can mediate SOD briefly.

Key words: SOD; TAT-SOD; neuronal apoptosis

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