肠出血性大肠杆菌Ⅲ型分泌系统调控因素的研究进展

Abstract

Abstract: Type Ⅲ secretion systems (T3SS) enable the injection of bacterial proteins through membrane barriers into host cells. This system is required for colonization of their ruminant reservoir hosts by enterohaemorrhagic Escherichia coli (EHEC) and might also be important for the etiology of disease in the incidental human host. T3SS of E. coli inject a cocktail of proteins into epithelial cells that enable bacterial attachment and promotes longer-term colonization in the animal. Here, we review recent progress in our understanding of the regulation of T3SS in EHEC, focusing on the induction and assembly of the T3SS, and the co-ordination of effector protein expression.

Key words: enterohaemorrhagic Escherichia coli; type Ⅲ secretion systems; effector protein

CLC Number:

S852.61

WEI Bo, LIU Ming-qiang, HUHE Baterer. Development of Regulation Factor of Type Ⅲ Secretion Systems in Enterohaemorrhagic Escherichia coli[J]. , 2012, 39(6): 161-164.

References

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Development of Regulation Factor of Type Ⅲ Secretion Systems in Enterohaemorrhagic Escherichia coli

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