›› 2012, Vol. 39 ›› Issue (6): 141-145.

Previous Articles     Next Articles

Research Progress on Galectin-1 and its Biological Functions

QIN Xin-xin1,2, SUN Hong-mei2, ZHAO Hai-ping2, CHU Wen-hui2, WANG Da-tao2, LI Chun-yi2   

  1. 1. Jingsu University of Science and Technology,Zhenjiang 212018,China;
    2. Key Laboratory of Special Economic Animal Molecular Biology,Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction, Ministry of Agriculture,Jilin Province State Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Wild Economic Animals and Plants,Chinese Academy of Agricultural Sciences,Jilin 132109,China
  • Received:2011-11-07 Online:2012-06-20 Published:2012-07-02

Abstract: Galectin-1,a molecular that has 14 ku,is one of the lectin family members. Being used as a diagnostic index of various cancers,Galectin-1 molecule has aroused wide interest as a new target molecule for the treatment of cancer. Besides,Galectin-1 plays various normal biological functions,such as cell growth,nerve repair,revascularization and cartilage formation. To data,little research has been done about Galectin-1 in the regeneration of deer antlers,although Galectin-1 may be indispensible in the processes during antler regeneration based on its unique function. Compared to tumour,antlers also grow fast and highly express Galectin-1,but antler tissue does not become cancerous,which could inspire us for cancer research. To develop a new cancer therapy and solve the mystery of deer antler regeneration,it is important to learn about the biological functions of Galectin-1 in both tumourogenesis and antler regeneration.

Key words: Galectin-1; antler regeneration; antler stem cells

CLC Number: