Abstract: Canine pyometra is a disease which caused by pus product in uterine cavity and abnormal endometrium secondary infection by pathogens. Genital dirty, breeding, postnatal infection or stillbirth, dystocia midwifery infection can cause disease. One case of dog, therapia in animal hospital of Guizhou University, confirmed the disease of pyometra with clinical examination and laboratory examination, surgery was taken and successful; isolation and identification of pathogen and drug sensitivity tests. The results showed that the pathogen was Escherichia, and the highest sensitive drug were Cephalothin, Cephalothin, Kanamycin, Gentamycin. These investigations provided an important reference data for diagnosis, prevention and early drug choices for this disease.

Key words: bitch; pyometra; diagnosis; treatment