›› 2011, Vol. 38 ›› Issue (3): 112-115.

• 生物技术 • Previous Articles     Next Articles

Biological Characterizations of Scrapie 263K Infected Hamster

LU Yun, ZHAO De-ming, YANG Li-feng   

  1. (China Agricultural University, TSE Lab., Beijing 100193, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-03-20 Published:2011-03-20
  • Contact: YANG Li-feng

Abstract: In this study, we intracerebrally (IC) inoculated scrapie 263K infected hamster brain homogenate into the healthy hamsters of Chinese breed, the biological characteristics of 263K prion strain were identified by the clinical symptoms, the pathological, immunohistochemical and Western blotting characteristics. Then the 263K prion hamster animal model was established, which is significant for us to study the prion disease in the future in China.

Key words: 263K; biological characteristics; prion; scrapie

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