Abstract: Recent advancements in sequencing and genotyping technologies have promoted a rapid revolution in methods for beef cattle selection. Genotyping assays efficiency has been improved greatly, from the past restriction fragment length polymorphism (RFLP) markers that were low-throughput, time consuming to the newest high-density single nucleotide polymorphism (SNP) assays. As the cattle genome sequence map and SNP map were finished, cattle genome wide selection that was based on the high density SNP chip became a new research hot for cattle breeding. This paper that based on the high density SNP chip on beef cattle breeding effects, reviewed high-density SNP chip technology, next generation sequencing and beef cattle genome wide selection of research. The paper also elucidated the high-density SNP chip for multiple breeds model construction of genome wide selection, and show it was extremely important that accurately predicting genomic breeding value.

Key words: high density SNP chip; beef cattle; genomic selection