China Animal Husbandry & Veterinary Medicine ›› 2010, Vol. 37 ›› Issue (8): 160-163.

• 疾病防治 • Previous Articles     Next Articles

Relation Study of Depletion of Clenbuterol in Swine Urine and Blood

SUN Ze-xiang1，BAO Wei-hua1，YANG Ting2，WU Yin-liang2，ZHAO Jian2，YU Xiao-hua1，ZHANG Li-xia3，SHI Ding-kang3，GUO Hai-bo4，LU Jin-long5，WU Chao-fang1，LI Jun3   

  1. (1.Ningbo City Bureau of Animal Husbandry and Veterinary,Ningbo 315012, China; 2.The Ningbo Academy of Agricultural Sciences, Ningbo 315040, China; 3.Agricultural Bureau of Ningbo Yinzhou District, Ningbo city of Zhejiang province,Ningbo 315040, China；4.Animal Husbandry and Veterinary Station of Qiuaixiang Town, Ningbo city of Zhejiang province,Ningbo 315042,China；5.Animal Husbandry and Veterinary Station of Wuxiang Town, Ningbo city of Zhejiang province,Ningbo 315044, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-08-20 Published:2010-08-20
  • Contact: WU Yin-liang

Abstract: The distribution and depletion of Clenbuterol in swine urine and blood after treatment with dietary Clenbuterol were studied. Ten pigs(60 kg±5.7 kg) were used to determine the residues and depletion of Clenbuterol in swine. Pigs were fed 4 mg/kg Clenbuterol HCl for fifteen consecutive days. Samples of urine and blood were collected to determine Clenbuterol concentrations by GC/MS. The results showed that the mean concentrations of Clenbuterol were 393 to 1131 μg/L in urine, and 6.8 to 22.1 μg/L in blood during feeding period. The concentrations of Clenbuterol were rapidly decreased. With a 19-day withdrawal period, the mean concentrations of Clenbuterol were 2.19 and 0.49 μg/L in urine and blood, respectively. Moreover, there was a significant positive correlation between the concentration of Clenbuterol in urine and the concentration of Clenbuterol in blood. The correlation coefficient was 0.9385 and 0.9402 during feeding period and withdrawal period, respectively.

Key words: urine; blood; Clenbuterol; depletion; relation study

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