Abstract: Compound Enrofloxacin injection has certain practical value in clinical. It can control effectively infection of the mycoplasmal pneumonia of swine(MPS) and alleviate the symptom, reduces the disease incidence rate and morality rate and make weight increase in a certain degree. The effect of Enrofloxacin and its combination with sulfadiazine sodium to MPS is more superior than only Enrofloxacin and only sulfadiazine sodium. This study used 2.5% compound Enrofloxacin to treat MPS of artificial infection by 0.08，0.04 and 0.12 mL/kg body weight. The optimal dose was 0.08 mL/kg body weight through intramuscular injection.

Key words: artifical infection; MPS; compound Enrofloxacin injection