利用重组杆状病毒表达口蹄疫病毒基因研究进展

›› 2009, Vol. 36 ›› Issue (10): 34-38.

• 生物技术 • Previous Articles Next Articles

Research Progress of Expression of Foot-and-mouth Disease Virus Genes by Recombinant Baculovirus

CAO Qian-qian^1,2, LIAO De-fang², LI Hua-chun²

(1.College of Animal Science, Yunnan Agriculture University, Kunming 650201, China; 2.Yunnan Animal Science and Veterinary Institute, Kunming 650224, China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-10-20 Published:2009-10-20

Abstract

Abstract: Baculovirus expression system is a new, high efficacy eukaryote expression system which is used widely on studies and development of novel vaccine, diagnosis reagents and new protein drugs. There are various reports on the expression of foot-and-mouth disease virus (FMDV) genes by using recombinant baculovirus to construct recombinant structure proteins and non-structure proteins of FMDV in insect cell, intend to produce proteins that the bioactivity is identical to their indigenous viral proteins. This review summarizes update progress of using recombinant baculovirus expressing FMDV structure proteins and non-structure proteins, and related difficulties and problems are raised here for discussion.

Key words: recombinant baculovirus; FMDV; gene expressing

CLC Number:

S852.65

CAO Qian-qian;LIAO De-fang;LI Hua-chun. Research Progress of Expression of Foot-and-mouth Disease Virus Genes by Recombinant Baculovirus[J]. , 2009, 36(10): 34-38.

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Research Progress of Expression of Foot-and-mouth Disease Virus Genes by Recombinant Baculovirus

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