Abstract: Twelve 10 to 20 days Holstein cows were selected and assigned to two groups randomly (there was no significant body weight change between 2 groups). Control group were fed milk, test group were fed replacement of milk. All the cows involved in were fed for 30 days. This experiment result showed that the average daily body weight gain of control group was 0.768 kg,test group was 0.841 kg, 0.073 kg higher than control group, but there was no significantly change between them; the rate of diarrhea of control group is 5.6%, the rate of diarrhea of test group is 3.8%, 32% lower than control group.

Key words: replacement of milk on calf; average daily body weight gain; rate of diarrhea