高寒草甸环境硒缺乏对牦牛血液生化指标及抗氧化系统功能的影响

doi:10.16431/j.cnki.1671-7236.2019.04.012

Abstract

Abstract:

In order to explore the etiology,diagnosis and treatment of the disease characterized by skeletal muscle damage in yak,mineral concentrations were determined on inductively coupled plasma atomic emission spectroscopy in soil,forage and tissue of yaks.Blood parameters,biochemical indicators and antioxidant indicators were determined on automatic hematology analyzer,biochemical analyzer and visible spectrophotometry.The results showed that concentrations of selenium in the soil and forage samples from the affected area were extremely significantly lower than those from the unaffected areas (P<0.01).The mean concentration of selenium in blood,liver and hair samples from the affected yaks were extremely significantly lower than those in unaffected yaks (P<0.01).The concentrations of Hb and RBC from the affected yaks were extremely significantly lower than those from the unaffected yaks (P<0.01).MDA,CPK,GPT,GOT,ALP,LDH,FT₄,T₄ and TSH from the affected yaks were extremely significantly higher than those from the unaffected yaks (P<0.01).SOD,CAT,GSH-Px,FT₃ and T₃ from the affected yaks were extremely significantly lower than those from the unaffected yaks (P<0.01).Treatment of affected yaks by injecting 0.1% sodium selenite and 5% vitamin E compound sterilized solution,the concentration of selenium in blood samples and blood serum antioxidant indexes from the treated group yaks were gradually returned to normal.The clinical symptoms disappeared.It indicated that yaks' muscle injury disease in this region was caused by selenium deficiency,mainly due to the low selenium content in soils and forage.The above results were important for further diagnose of yaks' selenium deficiency.

Key words: yaks; selenium deficiency; skeletal muscle injury; Qinghai Lake watershed area; mineral elements metabolic

CLC Number:

S823.85

HUO Bin, WU Ting, SONG Chunjie, SHEN Xiaoyun. Effects of Selenium Deficiency in Alpine Meadow on Blood Biochemical Indexes and Antioxidant Systems of Yaks[J]. , 2019, 46(4): 1053-1062.

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Effects of Selenium Deficiency in Alpine Meadow on Blood Biochemical Indexes and Antioxidant Systems of Yaks

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