口蹄疫表位疫苗的研究进展

doi:10.16431/j.cnki.1671-7236.2017.02.014

Abstract

Abstract:

Foot and mouth disease (FMD) is caused by foot-and-mouth disease virus (FMDV) and affects cloven hoofed animals,it is an acute and potent infectious disease which has caused great loss in some regions. Up to now, people still use vaccines to prevent and control FMD which has become the the popular ways. Prepared by virus'antigen epitopes and carried with multiple epitopes and helper epitope,the epitope-based vaccine against FMD which has caught people's attention to it owing to it has high safety and is easy to be manipulated and controlled.In recent years,the research based on epitope of FMDV has made great progress.Now we review the latest progress of the FMDV epitopes and the epitope-based vaccine against FMD in this paper, in order to provide relevant preferences for the development of the vaccines with high security and efficiency.

Key words: FMD; cytotoxic T cell epitope; epitope-based vaccine

CLC Number:

S852.659.6

LI Shi-fang, SHAO Jun-jun, CHANG Hui-yun. Research Progress on the Epitope-based Vaccine against Foot and Mouth Disease[J]. , 2017, 44(2): 396-401.

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Research Progress on the Epitope-based Vaccine against Foot and Mouth Disease

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