葛根对奶牛脂肪肝细胞生化指标的影响

doi:10.16431/j.cnki.1671-7236.2017.02.013

Abstract

Abstract:

To explore the acting mechanism of Pueraria extract on fatty liver hepatocytes in dairy cows. The hepatocytes in dairy cows were isolated by two-step collagenase perfusion method and observed. The hepatocytes cultured in vitro were treated with different concentrations of Pueraria extract. The activities and contents of ALT, AST, TG, SOD and MDA in the hepatocytes were detected by biochemical methods. Results showed that in the administration of Pueraria extract with the concentrations of 50,100 and 500 μg/mL could extremely significantly reduce the liver cells of ALT, AST, TG, TC, MDA activity and content, increase SOD activity (P < 0.01). The Pueraria extract had significantly therapeutic effect on dairy cows fatty liver of biochemical indexes. The mechanism might be related to regulate lipid metabolism and anti lipid peroxidation.

Key words: Pueraria; dairy cow fatty liver; hepatocyte; biochemical index

CLC Number:

S816.32

LIU Xiao-kun, TIAN Meng-yue, QIN Jian-hua, MA Yu-zhong. Effects of Pueraria on Biochemical Indexes of Fatty Liver Hepatocytes in Dairy Cows[J]. , 2017, 44(2): 391-395.

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Effects of Pueraria on Biochemical Indexes of Fatty Liver Hepatocytes in Dairy Cows

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