›› 2009, Vol. 36 ›› Issue (7): 171-174.

• 疾病防治 • 上一篇    下一篇

抗日本血吸虫药物的研究进展

张媛1,林瑞庆1,李晓燕2,赵光辉1   

  1. (1.华南农业大学兽医学院, 广州 510642; 2.华南农业大学农学院, 广州 510642)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-07-20 发布日期:2009-07-20
  • 通讯作者: 赵光辉

The Research Advances in the Drug of Anti-Schistosoma japonicum

ZHANG Yuan1, LIN Rui-qing1, LI Xiao-yan2, ZHAO Guang-hui1   

  1. (1.College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China;2.College of Agronomy, South China Agricultural University, Guangzhou 510642, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-07-20 Published:2009-07-20
  • Contact: ZHAO Guang-hui

摘要: 日本血吸虫是一种重要的人兽共患寄生虫,具有重要的公共卫生和社会经济意义,引起国内外学者的高度关注。作者综述了抗日本血吸虫药物的最新进展,重点综述了吡喹酮、青蒿素和硝硫氰胺的药物代谢、作用机制和临床应用,为日本血吸虫病的防治奠定理论基础。

关键词: 日本血吸虫; 药物代谢; 作用机制; 临床应用

Abstract: Schistosoma japonicum, one of important zoonotic parasite, has an important socio-economic and public healthy effect, which caused high attention of domestic and abroad scholar. The latest advance of medicine for S. japonicum was reviewed in this paper, especially for drug metabolism, mechanism of action and clinical application of praziquantel, artemisinin and nithiocyanamine, which settles rationale for prevention and cure of S.japonicum.

Key words: S. japonicum; drug metabolism; mechanism of action; clinical application

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