CC-Dp对伊犁马驹麦草采食量和血清激素的影响

›› 2014, Vol. 41 ›› Issue (10): 104-108.

CC-Dp对伊犁马驹麦草采食量和血清激素的影响

彭国亮¹, 杨云安¹, 张浩², 邓海峰³, 余雄¹

1. 新疆农业大学动物科学学院, 新疆肉乳用草食动物营养实验室, 新疆乌鲁木齐 830052;
2. 伊犁职业技术学院, 新疆伊宁 835000;
3. 新疆昭苏马场, 新疆昭苏 835602

修回日期:2014-08-25 出版日期:2014-10-20 发布日期:2014-10-29
通讯作者: 余雄
作者简介:彭国亮(1989―),男,新疆人,硕士生,研究方向:反刍动物营养。
基金资助:
“现代农业(奶牛)产业技术体系建设专项资金资助”(CARS-37);“十二五”国家科技支撑项目《牧区及农牧交错带奶牛健康养殖技术集成及产业化示范》(2012BAD12B09);《新疆肉牛安全高效饲养关键技术研究与示范》(2011BAD47B02);不同用途马高效、安全养殖共性技术研发(2012BAD45B01);自治区重大专项《新疆农区奶牛健康养殖及疫病防控技术推广与示范》(20101230694);新疆肉乳用草食动物营养实验室开放课题

Effect of CC-Dp on the Straw Intake and Serum Hormone of Yili Colt

PENG Guo-liang¹, YANG Yun-an¹, ZHANG Hao², DENG Hai-feng³, YU Xiong¹

1. Xinjiang Key Laboratory of Meat & Milk Production Herbivore Nutrition, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China;
2. Vocational and Technical College, Yining 835000, China;
3. Xinjiang Zhaosu Racecourse, Zhaosu 835602, China

Revised:2014-08-25 Online:2014-10-20 Published:2014-10-29

摘要/Abstract

摘要： 本试验旨在探讨日粮中添加CC-Dp对马驹麦草采食量和血清中摄食调控激素的影响。选取20匹17月龄健康无病、体况和采食量相近的伊犁马驹,采用单因素试验设计,随机分为4组,每组5匹,对照组饲喂基础日粮,试验Ⅰ、Ⅱ、Ⅲ组分别在基础日粮中添加500、1000、1500 mg/kg CC-Dp。预试期7 d,正试期30 d。结果表明,与对照组相比,试验Ⅱ组马驹麦草采食量在试验第1~15天显著提高(P<0.05),血清中胆囊收缩素(CCK)和γ-氨基丁酸(GABA)含量在试验进行1~15 d分别显著降低和升高(P<0.05);与对照组相比,试验Ⅲ组马驹麦草采食量在试验全期内显著提高(P<0.05),血清中CCK含量在试验进行1~15 d极显著降低(P<0.01)、16~30 d显著降低(P<0.05),血清中GABA含量在试验全期均显著提高(P<0.05);各组间血清中神经肽Y(NPY)、5-羟色胺(5-HT)、瘦素(LEP)含量差异均不显著(P>0.05)。综上所述,日粮中添加1500 mg/kg CC-Dp能显著提高伊犁马驹麦草采食量,显著降低血清中胆囊收缩素含量,显著升高血清中γ-氨基丁酸含量,推测其作用机制可能是通过降低动物体内胆囊收缩素水平以调控动物的采食,且与γ-氨基丁酸的调控途径有关。

关键词: 伊犁马驹; CC-Dp; 麦草采食量; 胆囊收缩素; γ-氨基丁酸

Abstract: This paper was conducted to investigate the effect of CC-Dp on the colts straw intake and regulation hormone in the serum.20 17-month-old healthy Yili female colts with similar body condition and intake were randomly divided into four groups and 5 colts in each group. The control group was fed with basic diet,groups Ⅰ,Ⅱ and Ⅲ were fed the basal diet supplemented with 500,1000,1500 mg/kg CC-Dp,respectively. Pre-trial period was 7 d,formally trial period was 30 d.The results showed that compared with the control group,the average straw intake in group Ⅱ was significantly increased during 1 to 15 days (P<0.05),the serum CCK and GABA contents was significantly decreased and increased during 1 to 15 days,respectively (P<0.05).Compared with the control group,the average straw intake in group Ⅲ was significantly increased in the whole period (P<0.05),the serum CCK content was extremely significantly decreased during 1 to 15 days (P<0.01),and was significantly decreased during 16 to 30 days (P<0.05),the serum GABA content was significantly increased in the whole period (P<0.05).The were no significant differences in the serum NPY,5-HT and LEP contents among all groups (P>0.05).In conclusion,the basal diet supplemented with 1500 mg/kg CC-Dp could significantly improve the straw intake,reduce the serum CCK content and increase the serum GABA content of colt. Speculated that the mechanism of CC-Dp in animal feed intake regulation was probably through reducing levels of CCK in vivo,and might be related with GABA regulatory pathways.

Key words: Yili colt; CC-Dp; straw intake; CCK; GABA

中图分类号:

S821.8⁺3

彭国亮, 杨云安, 张浩, 邓海峰, 余雄. CC-Dp对伊犁马驹麦草采食量和血清激素的影响[J]. , 2014, 41(10): 104-108.

PENG Guo-liang, YANG Yun-an, ZHANG Hao, DENG Hai-feng, YU Xiong. Effect of CC-Dp on the Straw Intake and Serum Hormone of Yili Colt[J]. , 2014, 41(10): 104-108.

参考文献

1 王九峰,李同洲.动物营养学[M].北京:中国农业大学出版社,2007.
2 王朝勇,杨琳.神经肽Y和瘦素对动物摄食行为的调控[J].畜牧与饲料科学,2010,31(9):28~29.
3 王迪铭.过瘤胃GABA的研制及其对奶牛生产性能的影响与机理研究[D].杭州:浙江大学,2013.
4 左伟勇,韩正康,王国杰.二丙谷酰胺对产蛋鸡摄食行为及内分泌的影响[J].中国家禽,2007,29(1):23~25.
5 刘华珍,彭克美.5-羟色胺(5-HT)摄食调节作用的研究进展[J].养殖与饲料,2005,12:9~12.
6 何田.瘦素、增食欲素、神经肽Y对摄食的影响[J].畜禽业,2008,228(4):23~25.
7 余冰,王丽,陈代文.含CCK抗体卵黄粉和二丙谷酰胺对生长猪生产性能、养分消化和内分泌激素的影响[J].中国畜牧杂志,2009,45(19):34~37.
8 赵茹茜,韩正康.灌服胰酶和二丙谷酰胺对鹅摄食活动的影响[J].南京农业大学学报,1993,16(3):74~78.
9 郭秀兰,王康宁,康仁勇.神经肽Y的促摄食作用及其调控[J].中国畜牧兽医,2005,32(4):6~9.
10 Collins S,Walker D,Forsyth P,et al.The effects of PGM on cholecystokjnin,bombesin,and glucagon induced satlety in the rat[J].Life Sci,1983,32(19):2223~2229.
11 Jensen R T.Cholecystokinin receptor antagonists:Ability to distinguish various classes of cholecystokinin receptors[M].New York:Academic Press INC,1990.
12 Pigueras L,Martinez V.Peripheral GABA_B agonists stimulate gastric acid secretion in mice[J].British Journal of Pharmacology,2004,142(6):1038~1048.
13 Shillabeer G,Davison J S.The cholecystokinin antagonist,PGM,increases food intake in the rat[J].Regul Pept,1984,8(3):171~176.
14 Shillabeer G,Davison J S.The effect of vagotomy on the increase in food intake induced by the cholecystokinin antagonist,PGM[J].Regul Pept,1985,12(2):91~99.
15 Smith G P,Greenberg D,Falasco J D,et al.Endogenous cholecystokjnin dose not decrease food intake or gastric emptying in fasted rats[J].Am J Physiol,1989,257:1462~1466.
16 Stratford T R,Kelley A E.Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control offeeding behavior[J].Journal of Neuroscience,1999,19(24):11040~11048.