传染性造血器官坏死病诊断及防控的研究进展

摘要/Abstract

摘要： 传染性造血器官坏死病(infectious hematopoietic necrosis,IHN)是一种严重危害冷水鱼养殖的病毒病,被列为国家二类动物疫病。作者就国内外对传染性造血器官坏死病病毒(IHNV)的生物学特征、感染的临床症状及流行特点、病毒基因组及其结构蛋白特征、检测诊断技术及防控等方面的研究进行探讨与综述, 旨在为该病的预防与控制提供资料。

关键词: 传染性造血器官坏死病; 检测技术; 防控措施

Abstract: Infectious hematopoietic necrosis(IHN) as the national second-class animal disease was a serious viral disease of cold-water fish. The following aspects of IHN were discussed and reviewed in this papers in order to provide the data for the prevention and control of the disease, such as biological characteristics, clinical symptoms and popular feature, the viral genome and structural protein characteristics,detection and diagnosis technology, the prevetion and control measures.

Key words: infectious hematopoietic necrosis; detection techology; prevention and control measures

中图分类号:

S941

徐立蒲, 王小亮, 杨丽文, 曹欢, 王静波, 王姝. 传染性造血器官坏死病诊断及防控的研究进展[J]. , 2013, 40(3): 209-215.

XU Li-pu, WANG Xiao-liang, YANG Li-wen, CAO Huan, WANG Jing-bo, WANG Shu. Researd Progress on the Diagnosis,Prevention and Control of Infectious Hematopoietic Necrosis[J]. , 2013, 40(3): 209-215.

参考文献

1 王光玉,陈雷,曲径,等.鱼类传染性造血组织坏死病(IHN)的病毒学特征和流行病学特点[J].水产科学,2007,26(5):303～306.
2 牛鲁祺,赵志壮.东北地区虹鳍IHN和IPN 流行病学的初步研究[J].水产学报,1988,12(4):327～332.
3 刘荭,范万红,史秀杰.国内养殖鱼类和进境鱼卵中传染性造血器官坏死病毒(IHNV)的检测及基因分析[J].华中农业大学学报,2006,25(5):544～549.
4 许建明,段向英,张念之,等.三重实时荧光RT-PCR检测三种鱼类弹状病毒的研究[J].检验检疫学刊,2009,19(1):5～10.
5 沈加丽,龚祖埙.弹状病毒研究的新进展Ⅰ:病毒的基因结构[J].中国病毒学,1997,12(2):103～111.
6 沈加丽,龚祖埙.弹状病毒研究的新进展Ⅱ:病毒的结构蛋白、转录、复制和核衣壳化的研究[J].中国病毒学,1998,13(4):282～291.
7 吴斌,孙铭,肇慧君.应用原位杂交技术检测感染斑马鱼体内的传染性造血器官坏死病毒[J].健康与生物医药,2011(7):217～218.
8 岳志芹,刘荭,梁成珠.实时定量RT-PCR检测鱼类传染性造血器官坏死病毒方法的建立与应用[J].水生生物学报,2008,32(1):91～95.
9 国家农业部.GB/T 15805.1淡水鱼类检疫方法第一部分[S].北京:中国标准出版社,1995.
10 赵志壮,牛鲁祺.应用ELISA方法快速检测IHNV-B病毒[J].水产学报,1993,17(1):61～63.
11 赵志壮,刘长明.分泌IHNV-B病毒单克隆抗体杂交瘤细胞的建立[J].中国水产科学,1994,1(1):73～75.
12 高隆英,史秀杰,刘荭,等.用RT-PCR法快速检测鲤春病毒血症病毒基因[J].水生生物学报, 2002,26:452～456.
13 铃木聪. ブリ腹水症ウイルスポリペプチドの抗原性の経时的出现およびその血清学的解析[J].鱼病研究(日),1995,30(3):209～214.
14 Alonso M,Chiou P P,Leong J A. Development of a suicidal DNA vaccine for infectious hematopoietic necrosis virus (IHNV) [J].Fish Shellfish Immunology,2011,30(3):815～823.
15 Arakawa C K, Deering R E, Higman K H,et al. Polymerase chain reaction (PCR) amplification of a nucleoprotein genesequence of infectious hematopoietic necrosis virus[J]. Disease of Aquatic Organisms,1990,8:165～170.
16 Arnzen J M,Ristow S S,Hesson C P,et al.Rapid fluorescent antibody tests for infectious hematopoietic necrosis virus (IHNV) utilizing monoclonal antibodies to the nucleoprotein and glycoprotein[J]. Journal of Aquatic Animal Health, 1991,3(2):109～113.
17 Bootland L M, Leong J C. Infectious hematopoietic necrosis virus.In: Woo P T K, Bruno D W (Eds).Fish diseases and disorders, volume 3, viral, bacterial and fungal infections, CAB international.Oxon,UK,1999.
18 Caipang C M, Haraguchi I, Ohira T, et al. Rapid detection of a fish iridovirus using loop-mediated isothermal amplification (LAMP)[J]. Journal of Virological Methods,2004,121(2):155～161.
19 Cox J H, Dietzschold B, Schneider L G. Rabies virus glycoprotein.Ⅱ.Biologicalnd serological characterization[J]. Infection and Immunity,1977,16(3):754～759.
20 Deering R E,Arakawa C K,Oshima K H,et al.Development of a biotinylated DNA probe for detection and identification of infectious hematopoietic necrosis virus[J].Dis Aquat Org,1991(11):57～65.
21 Dixon P R,Hill B J.Rapid detection of fish rhabdoviruses by the enzyme linked immnosorbent assay (ELISA)[J]. Aquaculture,1984,42:1～12.
22 Drolet B S, Rohovec J S, Leong J C.The route of entry and progression of infectious haematopoietic necrosis virus in Oncorhynchus mykiss (Walbaum):A sequential immunohistochemical study[J].Journal of Fish Diseases,1994,17(4):337～344.
23 Drolet B S, Chiou P P, Heidel J,et al. Detection of truncated virus particles in a persistent RNA virus infection in vivo[J].Journal of Virology,1995,69:2140～2147.
24 González M P,Sánchez X, Ganga M A,et al.Detection of the infectious hematopoietic necrosis virus directly from infected fish tissues by dot blot hybridization with a non-radioactive probe[J]. Journal of Virology Methods,1997,65(2):273～279.
25 Gunimaladevi I,Kono T,Venugopal M N,et al.Detection of koi herpesvirus in common carp, Cyprinus carpio L., by loop-mediated isothermal amplification[J]. Journal of Fish Diseases,2004,27(10):583～589.
26 Gunimaladevi I,Kono T,Lapatra S E,et al.A loop mediated isothermal amplification (LAMP) method for detection of infectious hematopoietic necrosis virus (IHNV) in rainbow trout(Oncorhynchus mykiss)[J].Archives of Virology,2005,150(5):899～909.
27 Kim H J,Oseko N,Nishizawa T,et al.Protection of rainbow trout from infectious haematopoietic necrosis (IHN) by injection of infectious pancreatic necrosis virus(IPNV) or poly(I:C)[J].Dis Aquat Org,2009,83:105～113.
28 Kim S Y,Kim S R, Oh M J,et al.In vitro antiviral activity of red alga,polysiphonia morrowii extract and its bromophenols against fish pathogenic infectious haematopoietic necrosis virus and infectious pancreatic necrosis virus[J].J Microbiol, 2011,49:102～106.
29 Kono T,Savan R,Sakai M,et al.Detection of white spot syndrome virus in shrimp by loop-mediated isothermal amplification[J]. Journal of Virological Methods,2004,115(1):59～65.
30 Lorenzen N,Lorenzen E,Einer Jensen K, et al.DNA vaccines as a tool for analyzing the protective immulle response against rhabdovimses in rainbow trout[J].Fish&Shellfish Immunology,2002(12):439～453.
31 OIE. Manual of diagnostic tests for aquatic animals[M].the OIE Aquatic Animal Health Standards Commission,2009.
32 Overturf K, LaPatra S, Powell M, et al. Real-time PCR for the detection and quantitative analysis of IHNV in salmonids[J]. Journal of Fish Diseases,2001,24(6):325～333.
33 Peñaranda M M,Purcell M K,Kurath G. Differential virulence mechanisms of infectious hematopoietic necrosis virus in rainbow trout (Oncorhynchus mykiss) include host entry and virus replication kinetics[J]. Journal of General Virology,2009,90(Pt9):2172～2182.
34 Peñaranda M M,Lapatra S E, Kurath M.Specificity of DNA vaccines against the U and M genogroups of infectious hematopoietic necrosis virus(IHNV) in rainbow trout(Oncorhynchus mykiss)[J].Fish Shellfish Immunoloyg,2011,31(1):43～51.
35 Ristow S S, Arnzen De Avila J. Monoclonal antibodies to the glycoprotein and nucleoprotein of infectious hematopoietic necrosis virus (IHNV) reveal differences among isolates of the virus by fluorescence, neutralization and electrophoresis[J].Diseases of Aquatic Organisms,1991,11(2):105～115.
36 Romero A,Figueras A,Thoulouze M I,et al.Recombiant infectious hematopoietic necrosis viruses induce protection for rainbow trout Oncorhynchus mykiss[J].Disease of Aquatic Organism,2008,80:123～135.
37 Romero A,Dios S,Bremont M,et al.Interaction of the attenuated recombinant rIHNV-Gvhsv GFP virus with macrophages from rainbow trout(Oncorhynchus mykiss)[J].Vet Immunol Immunopathol,2011(140):119～129.
38 Said T,Bruley H,Lamoureux A,et al. An RNA-binding domain in the viral haemorrhagic septicaemia virus nucleoprotein[J]. Journal of General Virology,1998,79(1):47～50.
39 St-Hilaire S,Ribble C S,Stephen C,et al. Epidemiological investigation of infectious hematopoietic necrosis virus in salt water net-pen reared Atlantic salmon in British Columbia,Canada[J]. Aquaculture,2002,212(1～4):49～67.
40 Thomas D,Newcomb W W,Brown J C,et al. Mass and molecular composition of vesicular stomatitis virus: A scanning transmission electron microscopy analysis[J].Journal of Virology,1985,54(2):598～607.
41 Winton J R,Einer-Jensen K.Molecular diagnosis of infectious hematopoietic necrosis and viral hemorrhagic septicemia.In: Cunningham C O,ed.Molecular diagnosis of Salmonid diseases.the Netherlands,2002.
42 Wolf K. Fish viruses and fish viral disease[M].New York,Cornell University Press,1988.

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