›› 2010, Vol. 37 ›› Issue (7): 194-198.

• 流行病防治 • 上一篇    下一篇

牛结核病诊断方法的研究进展

王金果1,刘爱林2,周向梅1,苑方重1,尹晓敏1,杨建民1,杨利峰1,赵德明1   

  1. (1.中国农业大学动物医学院,国家海绵状脑病实验室,北京 100193;2.河北省邯郸市动物疾病预防控制中心,邯郸 056005)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-07-20 发布日期:2010-07-20

The Advancement of Diagnostic Methods for Bovine Tuberculosis

WANG Jin-guo1, LIU Ai-lin2, ZHOU Xiang-mei1, YUAN Fang-zhong1, YIN Xiao-min1,
YANG Jian-min1, YANG Li-feng1, ZHAO De-ming1
  

  1. (1.College of Veterinary Medicine,China Agricultural University,National Animal TSE Laboratory, Beijing 100193, China;2.Handan Municipal Center for Disease Prevention and Control, Handan 056005, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-07-20 Published:2010-07-20

摘要: 牛结核病是由牛分支杆菌、结核分支杆菌、禽分支杆菌等引起的一类慢性消耗性疾病,是牛各种传染病中致死率最高的疾病之一,该病在人畜之间可以相互传染,很难根治,是影响养牛业和全人类健康的重大疾病,因此控制本病的传播和蔓延迫在眉睫。控制牛结核病的主要措施是及时检疫和根除病牛,定期对牛群进行检疫监控。近年来,随着生命科学的发展,进一步将传统细菌检测法、免疫学检测法和分子生物学检测法3种方法相结合,特别是分子水平上科学技术的发展,使牛结核病的诊断方法逐渐得到完善,同时获得了许多牛分支杆菌的特异性抗原及其基因,对于阐明结核分支杆菌和牛分支杆菌的分子进化和遗传变异规律等方面都具有重要的流行病学意义。

关键词: 牛结核病; 分支杆菌; 诊断方法

Abstract: BTB (Bovine tuberculosis) is series of chronic disease caused by Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium avian, et al. The lethality rate of BTB is one of the highest disease in all bovine transmissible diseases. It is very urgent to prevent and control the transimission and pervasion of this disease, since it can be transmited between domestic cattle and human and without effective treatment, which seriously affect the cattle industry and human health. The main measures of controlling BTB including in quanrantine cows on time and remove the infected cows. In recent years, with the development of life science, the traditional bacterial detection method, immunology detection and molecular biology methods are combined well together, particularly the development on molecular levels gradually improved the bovine tuberculosis of diagnostic method, meanwhile, many of specific Mycobacterium tuberculosis antigens and genes were found, which palyed a signifcant role in elucidating the molecular evolution and genetic variation of bovine tuberculosis Mycobacterium.

Key words: bovine tuberculosis; Mycobacterium; diagnosic method

中图分类号: