›› 2010, Vol. 37 ›› Issue (6): 192-193.

• 疾病防治 • 上一篇    下一篇

狼连涂擦剂急性毒性试验及微核试验

曲玲玲,田淑琴,高媛,张美玉,邓孝廷   

  1. (西南民族大学生命科学与技术学院 基础兽医学,成都 610041)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-06-20 发布日期:2010-06-20
  • 通讯作者: 邓孝廷

Acute Toxicity and Micronucleus Test of Lang-lian Embrocation

QU Ling-ling, TIAN Shu-qin, GAO Yuan, ZHANG Mei-yu,DENG Xiao-ting   

  1. (Southwest University for Nationalities, College of Life Science and Technology,The basis of Veterinary Medicine, Chengdu 610041, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-06-20 Published:2010-06-20
  • Contact: DENG Xiao-ting

摘要: 为检测狼连涂擦剂(以狼毒为君药,连翘为臣药的主方)的毒理学安全性,对试验小鼠进行半数致死量试验及微核试验。结果狼连涂擦剂LD50为3253.87 mg/kg,在小鼠骨髓嗜多染红细胞微核试验中未发现该药物对小鼠有遗传毒性,表明狼连涂擦剂的安全性良好。

关键词: 狼连涂擦剂; 急性毒性试验; 微核试验

Abstract: To detect toxicological Safety of Lang-lian embrocation, acute toxicity and micronucleus test were tested. LD50 of Lang-lian embrocation was 3253.87 mg/kg. Micronucleus test of bone marrow cells in mice lacked toxicity. The results showed that Lang-lian embrocation had good security.

Key words: Lang-lian embrocation; acute toxicity; micronucleus test

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