黄瓜子和生菜子提取物促进骨折愈合的试验研究

›› 2010, Vol. 37 ›› Issue (2): 125-128.

黄瓜子和生菜子提取物促进骨折愈合的试验研究

禇洪光，邓孝廷，田淑琴，谢秋菊

(西南民族大学生命科学与技术学院，成都 610041)

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-20 发布日期:2010-02-20

The Study of Cucumber and Lettuce Seed Powder Extract Promoting Fracture Healing

CHU Hong- guang， DENG Xiao- Ting， TIAN Shu- qin， ZHAO Qiu- ju， XIE Qiu- ju

(College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China)

Received:1900-01-01 Revised:1900-01-01 Online:2010-02-20 Published:2010-02-20

摘要/Abstract

摘要： 摘要：本试验主要研究黄瓜子和生菜子合用促进骨折愈合的作用及其初步机理。将蛋鸡60只，体重1.75～2.25 kg，造成右侧小腿中段横行闭合骨折模型，随机分为数目相等的高剂量组、中剂量组、低剂量组，阳性对照组和阴性对照组。试验组以不同比例的黄瓜子和生菜子提取物灌胃给药，阳性对照组以麝香接骨胶囊灌胃给药，阴性对照组以生理盐水灌胃，随后对各组进行动态观察、组织学观察、血清学观察和放射学观察。结果显示，黄瓜子和生菜子提取物中剂量组可促进全身代谢反应，提高血清碱性磷酸酶含量，加快血肿吸收机化，提高血钙、磷离子浓度，提高骨痂生成量和强度。结果表明黄瓜子和生菜子提取物可以通过提高钙、磷离子浓度，促进钙、磷向骨折断端转移而对骨折的愈合起到促进作用。

关键词: 关键词：黄瓜子; 生菜子; 骨折愈合; 鸡

Abstract: Abstract：To research the cucumber and lettuce’s combination to promote the role of fracture healing and the initial mechanism, 60 white broiler, weighing 1.75- 2.25 kg,were randomly divided into an equal number of high- dose group, middle dose group, low- dose group, positive control group and negative control group, then, to fracture the broiler’s middle of right leg to cause transverse closed fracture model. Different proportions of cucumber and lettuce seed powder extract were gavage feeding to experimental group. Musk bone capsule was gavage feeding to positive control group. Negative control group were fed with saline. Subsequently　each group were adopt dynamic observation, histological observation, serological and radiological observation. Experimental group that were fed middle dose of cucumber and lettuce seed powder extract could promote systemic metabolic response, increase serum alkaline phosphates' levels, speed up the absorption of hematoma, increased serum calcium and phosphorus concentration and improve the quantity and intensity of callus generation. The results showed that cucumber and lettuce can increase calcium and phosphorus concentration, promote calcium and phosphorus transfer to the fracture line to promote fracture healing.

Key words: Key words：Cucumber; Lettuce; fracture; broiler

禇洪光;邓孝廷;田淑琴;谢秋菊. 黄瓜子和生菜子提取物促进骨折愈合的试验研究[J]. , 2010, 37(2): 125-128.

CHU Hong- guang;DENG Xiao- Ting;TIAN Shu- qin;ZHAO Qiu- ju;XIE Qiu- ju. The Study of Cucumber and Lettuce Seed Powder Extract Promoting Fracture Healing[J]. , 2010, 37(2): 125-128.

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