不同吸附剂对黄曲霉毒素B1吸附效果的研究

›› 2009, Vol. 36 ›› Issue (8): 5-9.

• 动物营养与饲料科学 • 下一篇

不同吸附剂对黄曲霉毒素B₁吸附效果的研究

李娟娟，苏晓鸥

（中国农业科学院农业质量标准与检测技术研究所，北京 100081）

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-08-20 发布日期:2009-08-20
通讯作者: 苏晓鸥

The Study of Binding Efficacy of Different Adsorbents on Aflatoxin B₁

LI Juan-juan, SU Xiao-ou

(Institute of Quality Standard and Testing Technology for Agro-Product, Chinese Academy of Agricultral Sciences, Beijing 100081, China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-08-20 Published:2009-08-20
Contact: SU Xiao-ou

摘要/Abstract

摘要： 作者通过体外试验和动物饲养试验，研究3种吸附剂对黄曲霉毒素B₁（AFB₁）的吸附效果。3种吸附剂分别是吸附剂A（主成分为酵母培养物提取物）、吸附剂B（主成分为水合铝硅酸盐）、吸附剂C（为复合物，主成分为酵母培养物及水合铝硅酸盐）。体外试验研究pH为2.0、6.0、8.0的磷酸盐缓冲液（PBS溶液）、人工胃液和肠液环境下3种吸附剂对AFB1的吸附能力，比较pH 8.0条件下3种吸附剂对AFB1的结合速率。结果表明，各种条件下吸附剂B的吸附能力最强。pH 8.0条件下，吸附剂B在10 min内对AFB₁吸附率达到97.69%，且60 min内吸附率一直处在96.03%以上。吸附剂A和吸附剂C对AFB₁的作用效果较吸附剂B弱。动物饲养试验选择240只1日龄健康雄性AA肉仔鸡，随机分为8个处理，每个处理3个重复，每个重复10只鸡，饲养周期21 d。结果表明，与基础组相比较，AFB₁组（污染水平为98.8 μg/kg）肉仔鸡生长性能和肝脏功能发生显著变化，吸附剂A、B、C均能不同程度地缓解AFB₁对肉仔鸡生长性能和肝脏损伤方面的毒性作用，与吸附剂A、C相比，吸附剂B能更有效的防止肉仔鸡黄曲霉毒素B1中毒。结果提示，使用吸附剂B能很好的降低AFB₁对肉仔鸡的危害程度。

关键词: 吸附剂; AFB1; 吸附效果; 肉仔鸡

Abstract: The aim of this paper was to study the efficacy of three absorbents to sorb aflatoxin B₁(AFB₁). The main component of product A is yeast product, the main component of product B is HSCAS, and product C is the compound of yeast product and HSCAS. In vitro trial, AFB₁ binding capacity by three sorbents at different in vitro condition and AFB₁ binding speed by three sorbents at pH 8.0 in vitro condition were compared. Product B showed the highest in vitro affinity for AFB_1, and the rate of sorption reached to 97.69% in 10 min and it remained over 96.03% in 60 min at pH 8.0. Product A and product C did not showed so efficacy as product B. In vivo trial, a total of 240 broilers were assigned to 8 treatments (3 pens of 10 broilers per treatment). After 21 d, the aflatoxin-contaminated feed significantly decreased the growth performance and the liver function of broilers. The three products tested alleviated the adverse effects caused by aflatoxin, but compared with product A and C, product B could alleviate some of the toxic effects of AFB₁ more effectively.

Key words: absorbent; AFB₁; absorption efficacy; broilers

中图分类号:

S852.4^+4

李娟娟;苏晓鸥. 不同吸附剂对黄曲霉毒素B₁吸附效果的研究[J]. , 2009, 36(8): 5-9.

LI Juan-juan;SU Xiao-ou. The Study of Binding Efficacy of Different Adsorbents on Aflatoxin B₁[J]. China Animal Husbandry & Veterinary Medicine, 2009, 36(8): 5-9.

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不同吸附剂对黄曲霉毒素B₁吸附效果的研究

The Study of Binding Efficacy of Different Adsorbents on Aflatoxin B₁

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