›› 2009, Vol. 36 ›› Issue (3): 77-79.

• 生理生化 • 上一篇    下一篇

干扰素对鸡胚内H9N2亚型禽流感病毒滴度的影响

王新卫1,王玉1,李建中2,王艳1   

  1. (1.河南农业大学牧医工程学院, 郑州 450002; 2.河南省泌阳县畜牧局, 泌阳 463700)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-03-20 发布日期:2009-03-20

Effect of Interferon on Proliferation of H9N2 Avian Influenza Virus in Chick Embryo

WANG Xin-wei1, WANG Yu1, LI Jian-zhong2, WANG Yan1   

  1. (1.College of Animal Husbandry and Veterinary, Henan Agricultural University, Zhengzhou 450002, China;2. estock Bureau of Biyang County of Henan,Biyang 463700, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-03-20 Published:2009-03-20

摘要: 为探讨干扰素在动物上的运用,笔者利用H9N2亚型禽流感病毒与不同剂量干扰素(IFN)一起接种鸡胚,运用HA方法测定病毒效价,研究了干扰素干扰H9N2亚型禽流感病毒在鸡胚内增殖的情况,试验结果表明,高中低剂量干扰素都有抑制病毒增殖的作用,而3个试验组之间没有明显差异(P>0.05)。但是在一定的时间内,高剂量组干扰素与中低剂量组相比能够明显的抑制病毒增殖,表明高剂量组干扰素在一定时间内抑制H9N2禽流感病毒的作用比较明显,这在生产中有一定的应用价值。

关键词: 干扰素; 鸡胚; H9N2亚型禽流感病毒

Abstract: To investigate effect of interferon on proliferation of H9N2 avian influenza virus in chick embryo, chick embryos were grouped and treated with interferon and H9N2 avian influenza virus (AIV). And then virus titer was detected by using HA. The results showed that proliferation of AIV could be restrained in the high-dose group, middle-dose group and low-dose group, but there was no significant difference among the three treated groups. The high-dose group interferon could significantly inhibit the proliferation of the virus, which compared with other dose groups in a certain time. The results showed that the high-dose interferon inhibited the proliferation of H9N2 AIV obviously in a certain period of time, this would have a certain application value in the production.

Key words: interferon; chick embryo; H9N2 avian influenza virus

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