›› 2007, Vol. 34 ›› Issue (7): 69-71.

• 生物技术 • 上一篇    下一篇

α-银环蛇毒素单克隆抗体的研究进展

邱业峰1,2,贾艳1,李小兵1,罗胜军1,孙广瑞1,张志刚1,张乃生1,王哲1,谢光洪1   

  1. 1.吉林大学畜牧兽医学院,长春 130062; 2.军事医学科学院实验动物中心,北京 100071
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-07-20

The Research Development on Monoclonal Antibodies of α-BGT

QIU Ye feng1,2,JIA Yan1,LI Xianbing1,LUO Shengjun1,SUN Guangrui 1,ZHANG Zhigang1,ZHANG Naisheng1,WANG Zhe1,XIE Guanghong1   

  1. 1.College of Animal Science and Vcterinary Medicine,Jilin University,Changchun 130062,China;2.Laboratory Animal Center,The Academy of Military Medical Sciences,Beijing 100080,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-07-20

摘要: 作者介绍了α-银环蛇毒素(α-bungarotoxin,α-BGT)的特性、免疫原性、蛇毒抗血清作用及整体概况,并重点叙述了α-BGT单克隆抗体(monoclonal antibody,McAb)与抗血清相比的独特优势、α-BGT McAb的制备方法及αBGT McAb在医学、分子生物学和毒素检测上的应用现状及展望。提示制备α-BGT McAb及开发检测α-BGT试剂盒有较大的经济价值。

关键词: α-BGT; 抗血清; McAb

Abstract: The properties,immunogenicity,antiserum activity and the summary of α-BGT were described in the paper.And the specific advantages of α-BGT McAb were emphasized compared with antiserum.The system of manufacture of αBGT and its application and development on medicine,molccular biology,toxin detection were also showed,The paper declares that α-BGT kit is of significantly economic value.

Key words: α-BGT; antiserum; McAb

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