›› 2007, Vol. 34 ›› Issue (2): 100-101.

• 疾病防治 • 上一篇    下一篇

雏鸡脑软化症细胞免疫功能变化的研究

王奔,张宏玲,李艳飞   

  1. 东北农业大学动物医学院,哈尔滨 150030
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-02-20 发布日期:2007-02-20

The Cellular Immune Function of Chicken with Nutritional Encephalomalacia

WANG Ben, ZHANG Hongling, LI Yanfei   

  1. College of Animal Medicine,Northeast Agricultural University,Harbin 150030 China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-02-20 Published:2007-02-20

摘要: 以1日龄海兰蛋鸡为试验动物,用低VE水平且添加鱼油日粮饲喂雏鸡,复制脑软化症动物模型,研究脑软化症雏鸡血液白细胞数(WBC)、T淋巴细胞总数、T淋巴细胞酸性非特异性α-醋酸萘脂酶(ANAE+)及血清白介素-1β和白介素-2含量的变化。结果表明,患雏的WBC数、ANAE+T淋巴细胞总数、血清白介素含量均明显低于健康对照组雏鸡。结果说明,VE缺乏对雏鸡细胞免疫功能有明显的抑制作用。

关键词: 雏鸡; 脑软化症; 细胞免疫功能

Abstract: The number of the white blood cell(WBC),the sum total of lymphocytes ,the activity of T lymphocytes ANAE+ and the concentration of interleukins were studied by Acid αnaphthyl acetate esterase,(ANAE) dye method, and radio immunoassay(RIA) in the chicken with encephalomalicia induced by giving the feed being deficient in VE and extra fish oil artificially . The results showed that the number WBC,the sum total of lymphocytes and,activity of T lymphocytes ANAE+ and the concentration of IL1,IL2 in the ataxic chicks were significantly lower than that of the control group. The results indicated that vitamin E deficiency has evidently inhibited in the cellmediated immune functions of the chicken.

Key words: chicken; encephalomalicia; cellular immune function

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