安格斯母牛初乳产量与质量测定及其新生犊牛被动免疫效果评价

doi:10.16431/j.cnki.1671-7236.2022.09.009

中国畜牧兽医 ›› 2022, Vol. 49 ›› Issue (9): 3353-3361.doi: 10.16431/j.cnki.1671-7236.2022.09.009

安格斯母牛初乳产量与质量测定及其新生犊牛被动免疫效果评价

杨朝辉¹, 马雪连¹, 王凡¹, 易鹏飞¹, 吴静¹, 冯梦迪¹, 陈玉珠¹, 孙亚伟¹, 吾买尔江·牙合甫¹, 王胜², 许建标², 钟旗³, 周振勇⁴, 姚刚¹

1. 新疆农业大学动物医学学院, 乌鲁木齐 830052;
2. 新疆刀郎阳光农牧科技股份有限公司, 麦盖提 844600;
3. 新疆畜牧科学院兽医研究所, 乌鲁木齐 830000;
4. 新疆畜牧科学院畜牧研究所, 乌鲁木齐 830011

收稿日期:2022-02-28 出版日期:2022-09-05 发布日期:2022-08-24
通讯作者: 周振勇 E-mail:13699381790@163.com
作者简介:杨朝辉,E-mail:1186265895@qq.com。
基金资助:
新疆自治区乡村振兴产业发展科技行动项目（2020NC001）；肉牛高效健康饲养技术集成研究与示范（2021A02003-1）

Determination of Colostrum Yield and Quality of Angus Cows and Evaluation of Passive Immunity Effect of Newborn Calves

YANG Chaohui¹, MA Xuelian¹, WANG Fan¹, YI Pengfei¹, WU Jing¹, FENG Mengdi¹, CHEN Yuzhu¹, SUN Yawei¹, WUMAIERJIANG·Yahefu¹, WANG Sheng², XU Jianbiao², ZHONG Qi³, ZHOU Zhenyong⁴, YAO Gang¹

1. College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China;
2. Xinjiang Daolang Sunshine Agriculture and Animal Husbandry Technology Co., Ltd., Maigaiti 844600, China;
3. Institute of Veterinary Medicine, Xinjiang Academy of Animal Science, Urumqi 830000, China;
4. Institute of Animal Science, Xinjiang Academy of Animal Sciences, Urumqi 830011, China

Received:2022-02-28 Online:2022-09-05 Published:2022-08-24

摘要/Abstract

摘要： 【目的】新生犊牛被动免疫转移失败（failure of passive transfer，FPT）会导致犊牛发病率和死亡率显著增高，影响后期生长发育。本试验针对国外引进的安格斯母牛初乳产量和质量进行测定，并对其新生犊牛被动免疫效果进行评估，以期为新生犊牛初乳管理措施制定提供科学依据。【方法】随机选择健康安格斯初产母牛（24月龄）和经产母牛（36~48月龄）各15头，待母牛产犊后立即进行人工挤奶测定初乳产量、营养成分及免疫球蛋白浓度。选取初产和经产新生犊牛各15头，测定其初生重，分别采集犊牛出生后未食初乳（0 h）和食初乳后（24~36 h）血样，测定其血清总蛋白含量及各生理生化指标。【结果】初产母牛平均初乳产量极显著低于经产母牛，但其初乳中乳蛋白、非脂乳固体、乳糖、灰分含量，以及密度和电导率均极显著高于经产母牛（P<0.01）。初产母牛和经产母牛初乳中免疫球蛋白浓度分别为28.72%和26.24%，合格率分别为93.33%和91.67%，差异均不显著（P>0.05）；初产和经产新生犊牛被动免疫失败率分别为33.3%和25.0%；初产新生犊牛平均初生重极显著低于经产新生犊牛（P<0.01）；被动免疫成功犊牛平均初生重和球蛋白含量均极显著高于被动免疫失败犊牛（P<0.01）。【结论】新疆安格斯犊牛FPT的主要原因可能是母牛初乳产量低导致新生犊牛初乳摄入不足，初生重较低的犊牛FPT的风险性较高。本研究为制定切实可行的新生安格斯犊牛初乳补饲计划提供了科学基础。

关键词: 安格斯母牛; 新生犊牛; 初乳; 被动免疫转移失败(FPT)

Abstract: 【Objective】 The failure of passive transfer (FPT) of newborn calves will lead to significant increase in incidence rate and mortality rate of calves, and affect later growth and development.This study was aimed to measure the production and quality of colostrum of Angus cows imported from abroad, and evaluate the passive immunity effect of newborn calves, in order to provide a scientific basis for the formulation of colostrum management measures for newborn calves.【Method】 15 healthy Angus primiparous cows (24 months of age) and 15 Angus multiparous cows (36 to 48 months of age) were randomly selected, which were milked immediately after calving to determine the colostrum yield, nutritional component and immunoglobulin concentration.15 Angus primiparous and multiparous newborn calves were selected, respectively, the birth weight were measured, the blood samples were collected after birth without colostrum (0 h) and after colostrum (24 to 36 h) to determine the content of serum total protein and physiological and biochemical indicators.【Result】 The average colostrum yield of primiparous cows was extremely significantly lower than that of multiparous cows, but the contents of milk protein, non-fat milk solids, lactose, ash, and density and electrical conductivity of colostrum in primiparous cows were extremely significantly higher than that in multiparous cows (P<0.01).The immunoglobulin concentration of colostrum in primiparous and multiparous cows were 28.72% and 26.24%, the pass rate were 93.33% and 91.67%, respectively, there were no significant difference (P>0.05).The passive immunization failure rate of of primiparous and multiparous newborn calves were 33.3% and 25.0%, respectively.The average body weight of primiparous newborn calves was extremely significantly lower than that of multiparous newborn calves (P<0.01).The average birth weight and globulin content of passive immunity success calves were extremely significantly higher than that of passive immunity failure calves (P<0.01).【Conclusion】 The main cause of FPT in Xinjiang Angus calves might be closely related to the insufficient colostrum intake of newborn calves due to low colostrum production of cows.Calves with lower birth weight were at higher risk for FPT.This study provided a scientific basis for formulating a feasible colostrum supplementary feeding plan for newborn Angus calves.

Key words: Angus cows; newborn calves; colostrum; failure of passive transfer (FPT)

中图分类号:

S823.9

杨朝辉, 马雪连, 王凡, 易鹏飞, 吴静, 冯梦迪, 陈玉珠, 孙亚伟, 吾买尔江·牙合甫, 王胜, 许建标, 钟旗, 周振勇, 姚刚. 安格斯母牛初乳产量与质量测定及其新生犊牛被动免疫效果评价[J]. 中国畜牧兽医, 2022, 49(9): 3353-3361.

YANG Chaohui, MA Xuelian, WANG Fan, YI Pengfei, WU Jing, FENG Mengdi, CHEN Yuzhu, SUN Yawei, WUMAIERJIANG·Yahefu, WANG Sheng, XU Jianbiao, ZHONG Qi, ZHOU Zhenyong, YAO Gang. Determination of Colostrum Yield and Quality of Angus Cows and Evaluation of Passive Immunity Effect of Newborn Calves[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3353-3361.

参考文献

[1] HUANG Q S.How to improve the survival rate of milk calves[J].Insight-Veterinary Science, 2018, 1(1):18-22.
[2] LORENZ I, MEE J F, EARLEY B, et al.Calf health from birth to weaning.Ⅰ.General aspects of disease prevention[J].Irish Veterinary Journal, 2011, 64(1):10.
[3] CUTTANCE E L, MASON W A, LAVEN R A, et al.The relationship between failure of passive transfer and mortality, farmer-recorded animal health events and body weights of calves from birth until 12 months of age on pasture-based, seasonal calving dairy farms in New Zealand[J]. Veterinary Journal, 2018, 236:4-11.
[4] 李青.饲喂初乳对犊牛被动免疫失败率影响的探究[D].泰安:山东农业大学, 2014. LI Q.Study on effect of feeding colostrum on calves passive immunization[D].Tai'an:Shandong Agricultural University, 2014.(in Chinese)
[5] HUE D T, SKIRVING R, CHEN T, et al.Colostrum source and passive immunity transfer in dairy bull calves[J].Journal of Dairy Science, 2021, 104(7):8164-8176.
[6] HOMEROSKY E R, TIMSIT E, PAJOR E A, et al.Predictors and impacts of colostrum consumption by 4 h after birth in newborn beef calves[J].The Veterinary Journal, 2017, 228:1-6.
[7] GODDEN S.Colostrum management for dairy calves[J].Veterinary Clinics of North America Food Animal Practice, 2008, 24(1):19-39.
[8] ROBBERS L, JORRITSMA R, NIELEN M, et al.A scoping review of on-farm colostrum management practices for optimal transfer of immunity in dairy calves[J]. Frontiers in Veterinary Science, 2021, 8:797-807.
[9] 黄开武, 屠焰, 司丙文, 等.代乳品中不同来源蛋白质对哺乳期犊牛能氮代谢和免疫状况的影响[J].畜牧兽医学报, 2016, 47(9):1868-1878. HUANG K W, TU Y, SI B W, et al.Effect of protein with different sources in milk replacer on energy, nitrogen metabolism and immune state of suckling calf[J].Acta Veterinaria et Zootechnica Sinica, 2016, 47(9):1868-1878.(in Chinese)
[10] LAKRITZ J, TYLER J W, HOSTETLER D E, et al.Effects of pasteurization of colostrum on subsequent serum lactoferrin concentration and neutrophil superoxide production in calves[J].American Journal of Veterinary Research, 2000, 61(9):1021-1025.
[11] ARTYM J, ZIMECKI M, KRUZEL M L.Effect of lactoferrin on the methotrexate-induced suppression of the cellular and humoral immune response in mice[J] .Anticancer Research, 2004, 24(6):3831-3836.
[12] JASTER E H.Evaluation of quality, quantity, and timing of colostrum feeding on immunoglobulin G1 absorption in Jersey calves[J]. Journal of Dairy Science, 2005, 88(1):296-302.
[13] ARSLAN A, KAPLAN M, DUMAN H, et al.Bovine colostrum and its potential for human health and nutrition[J].Frontiers in Nutrition, 2021, 8:651721.
[14] 赵晓娥, 孙念琴, 宋爱爱, 等.不同月份产羔奶山羊初乳免疫球蛋白和常乳乳成分检测[J].家畜生态学报, 2018, 39(6):62-66. ZHAO X E, SUN N Q, SONG A A, et al.Detection of colostrum immunoglobulin and milk composition of dairy goats lambing in different months[J].Journal of Domestic Animal Ecology, 2018, 39(6):62-66.(in Chinese)
[15] PISELLO L, FORTE C, D'AVINO N, et al.Evaluation of Brix refractometer as an on-farm tool for colostrum IgG evaluation in Italian beef and dairy cattle[J].Journal of Dairy Research, 2021, 8(2):189-193.
[16] BUCZINSKI S, YANG L, CHIGERW M, et al.Systematic review and meta-analysis of refractometry for diagnosis of inadequate transfer of passive immunity in dairy calves:Quantifying how accuracy varies with threshold using a Bayesian approach[J].Preventive Veterinary Medicine, 2021, 189:105306.
[17] ABUELO A, CULLENS F, HANES A, et al.Impact of 2 versus 1 colostrum meals on failure of transfer of passive immunity, pre-weaning morbidity and mortality, and performance of dairy calves in a large dairy herd[J].Animals, 2021, 11(3):782.
[18] VIRTALA A, GRÖHN Y, MECHOR G D, et al.The effect of maternally derived immunoglobulin G on the risk of respiratory disease in heifers during the first 3 months of life[J].Preventive Veterinary Medicine, 1999, 39(1):25-37.
[19] TYLER J W, HANCOCK D D, WIKSIE S E, et al.Use of serum protein concentration to predict mortality in mixed-source dairy replacement heifers[J].Journal of Veterinary Internal Medicine, 1998, 12(2):79-83.
[20] BIELMANN V, GILLAN J, PERKINS N R, et al.An evaluation of Brix refractometry instruments for measurement of colostrum quality in dairy cattle[J]. Journal of Dairy Science, 2010, 93(8):3713-3721.
[21] RABOISSON D, TRILLAT P, CAHUZAC C.Failure of passive immune transfer in calves:A Meta-analysis on the consequences and assessment of the economic impact[J].PLoS One, 2016, 11(3):e0150452.
[22] BEAM A L, LOMBARD J E, KOPRAL C A, et al.Prevalence of failure of passive transfer of immunity in newborn heifer calves and associated management practices on US dairy operations[J].Journal of Dairy Science, 2009, 92(8):3973-3980.
[23] ALTVATER-HUGHES T E, HODGINS D C, WAGTER-LESPERANCE L, et al.Concentration and heritability of immunoglobulin G and natural antibody immunoglobulin M in dairy and beef colostrum along with serum total protein in their calves[J]. Journal of Animal Science, 2022, 100(2):skac006.
[24] DRIKIC M, WINDEYER C, OLSEN S, et al.Determining the IgG concentrations in bovine colostrum and calf sera with a novel enzymatic assay[J]. Journal of Animal Science & Biotechnology, 2018, 9:69.
[25] ALVES A C, ALVES N G, ASCARI I J, et al.Colostrum composition of Santa Inês sheep and passive transfer of immunity to lambs[J].Journal of Dairy Science, 2015, 98(6):3706-3716.
[26] 王祥, 张丹凤, 陆东林.奶牛初乳产量的测定[J].中国乳业, 2001, 12:32-33. WANG X, ZHANG D F, LU D L.Determination of colostrum yield in cows[J].China Dairy, 2001, 12:32-33.(in Chinese)
[27] MEIKLE A, KULCSAR M, CHILLIARD Y, et al.Effects of parity and body condition at parturition on endocrine and reproductive parameters of the cow[J].Reproduction, 2004, 127(6):727-737.
[28] 安涛.中国荷斯坦牛犊牛被动免疫水平和母牛初乳品质遗传分析[D].乌鲁木齐:新疆农业大学, 2021. AN T.Genetic analysis of passive immunity and colostrum quality of Chinese Holstein[D].Urumqi:Xinjiang Agricultural University, 2021.(in Chinese)
[29] WEAVER D M, TYLER J W, VANMETRE D C, et al.Passive transfer of colostral immunoglobulins in calves[J].Journal of Veterinary Internal Medicine, 2000, 14(6):569-577.
[30] MARTINEZ G B S, DE CARVALHO F G, CARVALHO S C S.Casein and whey protein in the breast milk ratio:Could it promote protein metabolism enhancement in physically active adults?[J].Nutrients, 2021, 13(7):2153.
[31] 封元, 马吉锋, 巫亮, 等.西门塔尔杂交母牛初乳成分及其对新生犊牛免疫的影响[J].畜牧与兽医, 2014, 46(11):65-68. FENG Y, MA J F, WU L, et al.Colostrum composition and its effect on immunity of newborn calves of Simmental crossbred cows[J].Animal Husbandry & Veterinary Medicine, 2014, 46(11):65-68.(in Chinese)
[32] VIRIATO R L S, QUEIRÓS M D S, MACEDO G A, et al.Design of new lipids from bovine milk fat for baby nutrition[J].Critical Reviews in Food Science and Nutrition, 2020, 62(1):11-15.
[33] MORRIN S T, LANE J A, MAROTTA M, et al.Bovine colostrum-driven modulation of intestinal epithelial cells for increased commensal colonisation[J]. Applied Microbiology and Biotechnology, 2019, 103(6):2745-2758.
[34] KOVÁCS A Z.The milking ability of Angus cows in comparison with their calves' growth[J].ActaAgraria Kaposváriensis, 1997, 50(1):45-57.
[35] 金天佑, 刘朋龙, 张红玉, 等.不同酸化奶对犊牛生长情况的影响[J].中国乳品工业, 2018, 46(2):23-25. JIN T Y, LIU P L, ZHANG H Y, et al.Effects of different conditions of acidified milk on growth of calves[J].China Dairy Industry, 2018, 46(2):23-25.(in Chinese)
[36] VITO V, ANA G C, DAVID A R, et al.Recent advances in phospholipids from colostrum, milk and dairy by-products[J].International Journal of Molecular Sciences, 2017, 18(1):173.
[37] NEWKIRK M, SHAKEEL F, PARIMI P, et al.Comparison of calorie and protein intake of very low birth weight infants receiving mother's own milk or donor milk when the nutrient composition of human milk is measured with a breast milk analyzer[J].Nutrition in Clinical Practice, 2018, 33(5):679-686.
[38] VASSEUR E, RUSHEN J, PASSILLÉ A.Does a calf's motivation to ingest colostrum depend on time since birth, calf vigor, or provision of heat?[J].Journal of Dairy Science, 2009, 92(8):3915-3921.
[39] BAXTER E M, JARVIS S, D'EATH R B, et al.Investigating the behavioural and physiological indicators of neonatal survival in pigs[J].Theriogenology, 2008, 69(6):773-783.
[40] 卢伟, 刘冲, 于青云, 等.不同初生重仔猪0~60日龄生长性能的比较[J].养猪, 2010, 6:11-13. LU W, LIU C, YU Q Y, et al.Comparison of growth performance of piglets with different birth weights from 0 to 60 days old[J].Swine Production, 2010, 6:11-13.(in Chinese)
[41] CORKUM A, TIAN Q, FERRUCCI L.Metabolomic signatures of high red blood cell distribution width[J].Innovation in Aging, 2020, 4(1):905.
[42] CARVALHO RONDÓ P H, CONDE A, SOUZA M C, et al.Iron deficiency anaemia and blood lead concentrations in Brazilian children[J].Transactions of the Royal Society of Tropical Medicine & Hygiene, 2011, 105(9):525-530.
[43] PASCUAL-FIGAL D A, BONAQUE J C, MANZANO-FERNÁNDEZ S, et al.Red blood cell distribution width predicts new-onset anemia in heart failure patients[J].International Journal of Cardiology, 2012, 160(3):196-200.
[44] MCGEE M, EARLEY B.Review:Passive immunity in beef-suckler calves[J].Animal, 2018, 13(4):810-825.

安格斯母牛初乳产量与质量测定及其新生犊牛被动免疫效果评价

Determination of Colostrum Yield and Quality of Angus Cows and Evaluation of Passive Immunity Effect of Newborn Calves

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	吴涛, 齐云霞, 刘伟, 朱洪龙, 黄冬维, 丁海生, 赵辉玲, 程广龙, 赵小伟. 基于蛋白质组学技术分析初乳和常乳摄入对初生犊牛肝脏蛋白表达的影响[J]. 中国畜牧兽医, 2023, 50(1): 37-45.
[2]	沃野千里, 高铎, 马峰涛, 金宇航, 刘茁, 孙鹏. 两种有机锌源对新生犊牛生长性能及锌代谢的影响[J]. 中国畜牧兽医, 2022, 49(9): 3382-3390.
[3]	和占星, 黄梅芬, 成玉梅, 张泉鹏, 张继才, 杨凯, 王安奎, 周亚平, 黄必志. 独龙牛和云岭牛初乳的理化特性比较[J]. 中国畜牧兽医, 2022, 49(6): 2156-2164.
[4]	张瑞, 周维强, 马越, 吴建平, 雷赵民. 牛至精油和初乳复合物对机会猪生长性能、血清抗氧化和免疫指标的影响[J]. 中国畜牧兽医, 2022, 49(4): 1314-1321.
[5]	宁景扬, 马龙刚, 陈紫薇, 安涛, 常瑶, 王凯, 王磊, 陈少侃, 张帆, 郭刚, 张海亮, 王雅春. 中国荷斯坦牛干奶期长度的群体特征及其与生产性能的关系[J]. 中国畜牧兽医, 2021, 48(9): 3368-3377.
[6]	翁秀秀, 刘欣欣, 乐祥鹏, 李万宏, 李发弟. 基于双向电泳技术研究湖羊初乳和常乳乳蛋白质组差异[J]. 中国畜牧兽医, 2021, 48(3): 865-872.
[7]	刘欢欢, 郭雁华, 张巧娥, 封元, 梁小军. 不同共轭亚油酸水平对淘汰安格斯母牛血清生化指标和肌肉脂肪酸的影响[J]. 中国畜牧兽医, 2019, 46(12): 3581-3589.
[8]	刘根涛, 卜登攀, 赵连生, 张巧娥. 巴氏初乳对犊牛生长性能及胃肠道发育的影响[J]. 《中国畜牧兽医》, 2017, 44(6): 1714-1719.
[9]	朱勇, 余思佳, 包健, 徐建雄. 发酵鲜食大豆秸秆对母羊繁殖性能、初乳品质及消化性能的影响[J]. 《中国畜牧兽医》, 2017, 44(1): 100-105.
[10]	王超丽，剡根强，王静梅，高家登，杨龙龙，杨铭伟. 抗犊牛肺炎支原体免疫初乳乳清的制备[J]. 中国畜牧兽医, 2014, 41(8): 85-90.
[11]	陈瑞芳，郭傲民,耿丹，张海燕，王士长. 水牛初乳粉和常乳粉对新生仔猪小肠组织形态结构的影响[J]. 中国畜牧兽医, 2014, 41(4): 137-143.
[12]	刘维华, 赵娟, 王瑜, 马静, 陈海燕. 浅析牛初乳的营养作用及潜在危害[J]. , 2013, 40(S1): 125-127.
[13]	李卫真;杨忠;张永云;苗永旺;王绍卿;汤守锟;田建云;李洁玉. 水牛初乳和常乳主要组分的动态变化[J]. , 2011, 38(8): 209-212.
[14]	李萍萍;戴鑫鑫;吴元昌; 蒋新环 . 奶牛初乳对细毛羊非繁殖季节发情的影响[J]. , 2008, 1(8): 143-144.
[15]	滑静;杨柳;万善霞;张淑萍. 牛初乳免疫球蛋白对仔猪血清IgG含量和增重的影响[J]. , 2008, 1(4): 127-128.