哺乳动物卵母细胞凋亡机制研究进展

doi:10.16431/j.cnki.1671-7236.2016.12.027

《中国畜牧兽医》 ›› 2016, Vol. 43 ›› Issue (12): 3263-3267.doi: 10.16431/j.cnki.1671-7236.2016.12.027

哺乳动物卵母细胞凋亡机制研究进展

马鲜平, 毕俊萱, 龙安格, 陈奕熹, 滕果洲, 易华山

西南大学荣昌校区动物医学系, 重庆 402460

收稿日期:2016-04-15 出版日期:2016-12-20 发布日期:2016-12-22
通讯作者: 易华山 E-mail:dyxyihuashan@swu.edu.cn
作者简介:马鲜平(1981-),女,甘肃文县人,硕士,讲师,研究方向:家畜解剖学及组织胚胎学,E-mail:xianpingma@126.com
基金资助:
中央高校基本业务费专项资金资助项目（XDJK2013C139、XDJK2015C032）

Advance of Apoptotic Mechanism in Mammalian Oocyte

MA Xian-ping, BI Jun-xuan, LONG An-ge, CHEN Yi-xi, TENG Guo-zhou, YI Hua-shan

Department of Animal Medicine, Rongchang Campus of Southwest University, Chongqing 402460, China

Received:2016-04-15 Online:2016-12-20 Published:2016-12-22

摘要/Abstract

摘要：

细胞凋亡是细胞程序性死亡过程，在生殖细胞的发生过程中具有重要作用。哺乳动物卵母细胞在生长发育过程中，除排卵受精的成熟卵母细胞外，其他卵母细胞在卵泡发育的不同阶段凋亡。作者综述了卵母细胞的发育与细胞凋亡、细胞凋亡的主要参与分子及凋亡途径等研究进展，旨在为进一步研究哺乳动物卵母细胞的生长、发育和排卵机制提供帮助。

关键词: 线粒体; 死亡受体; 卵母细胞; 细胞凋亡

Abstract:

Apoptosis is programmed cell death process, which plays an important role in the process of development of germ cells. In the process of growth and development of mammalian oocytes, in addition to the mature ovulation fertilization of the oocytes, the others are apoptotic at different stages of follicular oocytes. This paper summarizes the research progress of development of the main apoptosis mechanism and apoptosis pathway of mammalian oocytes, and lays a foundation for further studying growth, development and ovulation mechanism of oocytes.

Key words: mitochondria; death receptors; oocyte; apoptosis

中图分类号:

Q952

马鲜平, 毕俊萱, 龙安格, 陈奕熹, 滕果洲, 易华山. 哺乳动物卵母细胞凋亡机制研究进展[J]. 《中国畜牧兽医》, 2016, 43(12): 3263-3267.

MA Xian-ping, BI Jun-xuan, LONG An-ge, CHEN Yi-xi, TENG Guo-zhou, YI Hua-shan. Advance of Apoptotic Mechanism in Mammalian Oocyte[J]. , 2016, 43(12): 3263-3267.

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哺乳动物卵母细胞凋亡机制研究进展

Advance of Apoptotic Mechanism in Mammalian Oocyte

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