Abstract: The purpose of the experiment was the seasonal variations investigation and drug test on coccidial infected sheep in Xinjiang Urumqi.To count infection rate and infection intention of coccidia by using the saturated solution floating method and MacMaster's method.We carried out drug test by using sulfadimidine, counted reduction ratio and negative transformation rate of oocysts and analysied the average OPG of adult sheep and lamb after sulfadimidine treatment by SPSS 17.0.The result showed that the overall prevalence of coccidial infection was 71.38%, the infection rate of summer was 65.28%, the infection rate of autumn was 78.24%, the infection rate of winter was 62.18%, the infection rate of spring was 81.58%;There was the highest infection rate of lamb;Seven species were identified by morphological analysis.The infection rate of sheep which infected by one kinds of coccidia was 42.75%, 2 to 4 kinds of coccidia was 53.94%, more than 5 kinds was 3.31%.The best effect of insecticide was high dose group, whose oocyst decrease rate and negative rate was better than the medium and low dose groups.Meanwhile, lamb using low dose could achieve obvious repellent effect.In order to treat the coccidial infected sheep in Xinjiang Urumqi, we could use the sulfadimidine to do the anthelmintic work of lamp in spring and autumn.

Key words: Urumqi; sheep; coccidia; infection; seasonal variations