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Study on the Effect of Hedyotis diffusa Willd Superfines Powder on Immune Function in Mice

WANG Hang, TANG Cheng, YUE Hua, WANG Hong-ge   

  1. (School of Life Science and Technology, Southwest University for Nationalities,Chengdu 610041, China)
  • Received:2013-07-22 Online:2014-03-20 Published:2014-05-15

Abstract: The assay was aimed to study the effect of Hedyotis diffusa Willd superfines powder on immune function. Three groups of mice were gavaged with the drugs at doses of 1.75,1.25 and 0.75 g/kg once a day for 7 consecutive days, repectively. The mice of control group were administered with the same volume of saline.At the last time, mice were injected into the muscle with Newcastle disease vaccine,and get peripheral blood on days 7, 14 and 21 after the medicine administration. The enhancement of innate immune responses were evaluated by using CCK-8 method, hemagglutination inhibition test, macrophage phagocytic function test and organ coefficient method. The levels of lymphocytes proliferative capacity, serum antibody, peritoneal macrophage phagocytosis and the indexes of immune organs in mice were extremely significantly enhanced (P<0.01). Hedyotis diffusa dWilld superfines powder could extremely significantly regulate the immunity function of mice (P<0.01).

Key words: Hedyotis diffusa Willd; superfines powder; mouse; immune function