口蹄疫病毒完整病毒粒子定量方法的研究进展

Abstract

Abstract: The effective component of FMD vaccine is the whole virus particles of FMDV. The potency of vaccine is correlated to the amount of the 146S in the vaccine. It is very important to detection and quantification 146S in the vaccine and during the process of vaccine producing. Currently, the main method is ultra speed centrifugation. In addition, ELISA is concerned more and more. In the same time, many researchers are exploring other methods that may be simpler and faster. In this paper, various methods are introduced.

Key words: FMD vaccine; FMDV; 146S

CLC Number:

S852

LIU Yan-xia, ZHANG Gui-gang. Development of Quantification Methods of Foot and Mouth Disease Virus Whole Virus Particles[J]. .

References

1 卢永干,王伟峰,刘玉梅,等.蔗糖密度梯度紫外光定量法检测口蹄疫抗原146S含量的方法:中国,101655452.2010-02-24.

2 李乐,苗海生,信爱国,等.ELISA用于口蹄疫病毒146S抗原快速定量的研究[J].中国预防兽医学报, 2008,30(4):314~317.

3 苗海生,李乐,廖德芳,等.二辛可宁酸试剂定量蛋白质与口蹄疫抗原的研究[J].中国畜牧兽医, 2008,35(4):84~86.

4 殷震,刘景华.动物病毒学[M].第2版.北京:科学出版社,1997.

5 董金杰,祁光宇,刘学荣,等.用蔗糖密度梯度离心法检测与定量口蹄疫病毒抗原.第三届中国兽药大会－兽医生物制品学、兽医微生物学学术论坛文集,2010.

6 Abu Elzein E M E, Crowther J R. The specific detection of foot and mouth disease virus whole particle antigen(140S) by enzyme labeled immunosorbent assay[J]. J Hyg Camb, 1979,83:127~134.

7 Bachrach H L, Moore D M, McKercher P D. Immune and antibody responses to an isolated capsid protein of foot and mouth disease virus[J].Immol, 1975,115:1636~1641.

8 Barteling S J, Meloen R H. A simple method for the quantification of 140S particles of foot and mouth disease virus[J]. Arch Ges Virusforsch, 1974,45:362~364.

9 Brown F, Newman J F E. In vitro measurement of the potency of inactivated foot and mouth disease vaccines[J].J Hyg Camb, 1963,61:345~351.

10 Crowther J R, Abu Elzein E M E. Detection and quantification of foot and mouth disease virus by enzyme labelled immunosorbent assay techniques[J].J Gen Virol, 1979,42:597~602.

11 Crowther J R, Reckziegel P O, Prado J A. Quantification of whole virus particles (146S) of foot-and-mouth disease virus in the presence of virus subunits(12S), using monoclonal antibodies in a sandwich ELISA[J]. Vaccine, 1995,13(12):1064~l075.

12 Doel T R, Collen T. Quantitative assessment of 146S particles of foot and mouth disease virus in preparations destined for vaccines[J].J Biol Stand, 1982,10:69~81.

13 Doel T R, Mowat G N. An international collaborative study on foot and mouth disease virus assay methods. 2. Quantification of 146S particles[J]. Journal of Biological Standardization, 1985,13:335~344.

14 Fayet M T, Fargeaud D, Louisot P, et al. Ioumiantzeff :Mesure physico-chimique des particules 140S du virus de la fievre aphteuse[J]. Ann Inst Pasteur, 1971,121:107~118.

15 Jackson T, King A M, Stuart D I, et al. Structure and receptor binding[J]. Virus, 2003,91:33~46.

16 Kleid D G, Yansura D, Small B, et al. Cloned viral protein for food-and-mouth disease responses in cattle and swine[J]. Science, 1981,214:1125~1129.

17 Marcelo A S, Ignacio Fernández, Erika S, et al. Foot and mouth disease (FMD) virus: quantification of whole virus particles during the vaccine manufacturing process by size exclusion chromatograph[J].Vaccine, 2011,29:7182~7187.

18 Mateu M G. Antibody recognition of picornaviruses and escape from neutralization: a structure view[J].Virus Res, 1995, 38:1~24.

19 Ouldridge J E, Barnett P V, Hingley P J, et al. An indirect enzyme labelled immunosorbent assay for the detection of foot and mouth disease virus immunizing antigen in tissue culture harvests[J]. J Biol Stand, 1984,12:339~351.

20 Pay T W F, Hingley P H, Radlett P J. The correlation of 140S antigen dose with the serum neutralisation antibody response and with protection from challenge induced by FMD vaccine[J]. Vaccine,1987,5(1):60~64.

21 Thomas A A M, Woortmeijer R J, Puyck W, et al. Antigenic sites on foot and mouth disease virus type A10[J]. J Virol, 1988, 62:2782~2789.

22 Van Mannen C, Terpstra C. Quantification of intact 146S foot and mouth disease antigen for vaccine production by a double antibody sandwich ELISA using monoclonal antibodies[J].Biologicals, 1990,18:315~319.

23 Wild T F, Brown F. Nature of the inactivating action of trypsin on foot and mouth disease virus[J].J Gen Virol, 1967,1:247~250.

24 Yang M, Holland H, Clavijo A. Production of monoclonal antibodies against whole virus particles of foot-and-mouth disease virus serotype O and A and their potential use in quantification of intact virus for vaccine manufacture[J]. Vaccine, 2008,26:3377~3382.

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Development of Quantification Methods of Foot and Mouth Disease Virus Whole Virus Particles

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