p53和TGF-β在细胞生长调控中的相互作用及其与疾病的研究进展

China Animal Husbandry & Veterinary Medicine ›› 2012, Vol. 39 ›› Issue (4): 73-75.

• 生物技术 • Previous Articles Next Articles

Research on Interaction and Diseases between p53 and TGF-β in Regulation of Cell Growth

ZHENG Yan-sheng, ZHENG Shi-min, GAO Xue-li

College of Animal Medicine, Northeast Agricultural University, Harbin 150030,China

Received:2011-08-21 Revised:1900-01-01 Online:2012-04-20 Published:2012-04-20

Abstract

Abstract: p53 is the first discovered member of tumor suppression protein family, which can sense many cell signals to regulate cell proliferation, apoptosis and differentiation. TGF-β is a important physiological and biochemical regulator in organism which plays a important role in cell growth, differentiation, embryonic development, damage repair and so on. p53 has a close relationship with TGF-β signaling pathway. The relationship of p53 and TGF-β in cell growth regulation in latest years were reviewed.

Key words: p53; TGF-β; cell growth regulation

CLC Number:

Q813

ZHENG Yan-sheng;ZHENG Shi-min;GAO Xue-li. Research on Interaction and Diseases between p53 and TGF-β in Regulation of Cell Growth[J]. China Animal Husbandry & Veterinary Medicine, 2012, 39(4): 73-75.

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