Abstract: Foodborne pathogens are the most important pathogenic factors causing foodborne diseases in animals and humans.Common foodborne pathogens include Salmonella, diarrheagenic Escherichia coli,Campylobacter,Vibrio parahaemolyticus,Shigella and Staphylococcus aureus.Due to their strong invasion and colonization ability,these bacteria can contaminate a variety of fruits and vegetables and animal-derived foods,and spread through the “farm-to-table chain”.Due to the abuse of antibiotics,these bacteria have developed resistance to antibiotics,which makes it difficult for traditional antibiotics to deal with the increasingly serious bacterial resistance problem,thus making the treatment of foodborne bacterial infections faced with many challenges such as limited drug selection,poor bioavailability and difficult toxicity control.With the development of nanotechnology,various micro/nanomaterials have been gradually applied in the field of biomedicine,and have shown excellent therapeutic effects.Micro/nanomaterials mainly refer to a series of composite materials with an average particle size at the micron or nano level.In the treatment of foodborne pathogens,micro/nanomaterials are mainly drug delivery systems formed by combining micron and nano materials,which have the advantages of micron and nano scale materials,and have good biocompatibility,targeted drug delivery,controllable long-term release,and multiple antibacterial effects.The authors summarize the basic concepts,common types,special advantages and progress in the treatment of different foodborne pathogens of micro/nanomaterials.It also discusses the application potential and current challenges of micro/nanomaterials in solving various foodborne bacterial infections and alleviating antibiotic resistance,which will help promote the further exploration and application of micro/nanomaterials in the treatment of foodborne cell infections.

Key words: foodborne pathogens; nanomaterials; micromaterials; micro/nanomaterials