Fosl2基因的研究进展

Abstract

Abstract: Fosl2 (Fos-like antigen 2) that is expressed in a wide range of tissues during animal development belongs to the activator protein-1(AP1) transcription factor family that includes the various isoforms of Fos and Jun, which play diverse and important roles in animal growing development and immunologic response. Following the indepth research of recent years, people found that Fosl2 has a very close relationship with animal fat metabolism, skeleton development and cancer growth. This article reviewed the gene structure and the tissue distribution, also generalized the function of Fosl2 in animal fat metabolism, skeleton development, cancer growth and eye development. The prospects in study on the biological function were discussed in order to show a clearly direction for the deeper study and the animal growth traits promotion.

Key words: Fosl2 gene; tissue expression and gene structure; fat metabolism; skeleton development; biological function

FAN Xing-xing, LI Xin-jian, GUO Ji-li, LI Gai-ying, LV Gang, REN Guang-zhi. Research Progress of Fosl2 Gene[J]. .

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Research Progress of Fosl2 Gene

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