Biological Function and Extraction Process of Glycyrrhizic Acid and its Application in Monogastric Animal
SUN Huan-lin1,ZHANG Wen-ju1,LIU Yan-feng1,2,TANG Shu-zhen2
1.College of Animal Science and Technology,Shihezi University,Shihezi 832003,China;2.Xinjiang Academy of Animal Feed Research Institute,Urumqi 830000,China
SUN Huan-lin,ZHANG Wen-ju,LIU Yan-feng,TANG Shu-zhen. Biological Function and Extraction Process of Glycyrrhizic Acid and its Application in Monogastric Animal[J]. .
1 王惠敏.甘草药理作用及其临床应用[J].天津中医学院学报,2004(4):184~185.2 王瑛,吴萍.复方土金颗粒中甘草酸提取工艺研究[J].甘肃医药,2012,31(7):500~502.3 王海峰,邱芳萍.甘草中甘草酸的提取工艺研究[J].长春工业大学学报,2010,31(1):66~69.4 王百军,徐庆娟.氨性乙醇溶液从甘草中提取甘草酸工艺研究[J].辽宁华工,2009,38(9):620~622.5 刘萍,陈苗苗,乔莉萍,等.猪繁殖与呼吸综合征病毒致病机理的研究进展[J].中国畜牧兽医,2010,37(1):158~160.6 孙娜,赵昕,白元生,等.甘草酸二钾体外抗猪繁殖与呼吸综合征病毒(PRRSV)的活性[J].中国兽医学报,2013,33(2):282~286.7 邢玉娟,陈玉库,胡元亮,等.7种中药成分对新城疫病毒感染鸡胚成纤维细胞能力的影响[J].中国兽医杂志,2011,47(9):46~48.8 吴瑛,袁守亮,卢世林.甘草作为兽用药和饲料的应用研究[J].饲料研究,2006(9):18~21.9 吴华,张辉,段启辉.甘草药渣对放牧肉鸡肉品质的影响[J].青海大学学报,2010,28(3):58~61.10 宋美琴,牛丽,白元生,等.甘草酸二钾体外抗鸡传染性法氏囊炎病毒的作用机制[J].中国兽医科学,2010,42(6):642~646.11 张泽生,崔翠翠,孙宇.甘草酸对小鼠酒精性肝损伤的保护作用[J].食品科技,2009,34(5):225~227.12 张瑞,赵景辉,王英平,等.甘草残渣、关苍术茎叶对番鸭生产性能和免疫性能的影响[J].特产研究,2011(3):19~21.13 李文燕.乌拉尔甘草有效成分动态变化的研究[D].保定:河北农业大学,2012.14 杜文彬,张洪.甘草中甘草酸的提取工艺研究[J].安徽农业科学,2008,36(25):10935~10946.15 杜景娇,薛强,邹明强,等.新城疫检测技术的研究新进展[J].中国畜牧兽医,2012,39(2):187~191.16 陈红.甘草药理作用概述[J].海峡药学,2005,17(4):37~41.17 陈申秒,朱秀高,马景霞,等.鸡传染性法氏囊病疫苗免疫保护试验观察[J].中国畜牧兽医,2011,38(2):247~249.18 郑永利.甘草及甘草制剂的临床应用研究进展[J].内蒙古中医药,2009(9):74~75.19 卓立宏,黄群增,郭应臣.铜铁甘草酸配合物的合成及其抗氧化活性研究[J].化学研究与应用,2008,20(7):869~871.20 国家医药管理局中草药情报中心站.植物药有效成分手册[M].北京:人民卫生出版社,1986.21 姜举娟.PRRSV HuB1株的分离鉴定及甘草酸体外抗PRRSV感染的研究[D].哈尔滨:东北林业大学,2009.22 高鸿霞,邵世和,王国庆.中药甘草研究进展[J].井冈山医专学报,2004,11(5):8~11.23 高焕,杨淑娟,郭利伟,等.甘草多糖和甘草酸对NDV感染鸡胚成纤维细胞能力的影响[J].畜牧与兽医,2010,42(10):19~23.24 黄惠莲,周燕双,宋丽莉.不同提取工艺下甘草提取物中甘草酸铵含量测定研究[J].中国当代医药,2011,18(33):47~50.25 曹丽萍,蒲小红,刘美佑,等.甘草中甘草酸的提取工艺优化研究[J].广州化工,2009,37(7):94~95.26 潘国石.甘草酸生产工艺[J].基层中药杂志,2000,14(5):8~9.27 Aarestrup F M,Seyfarth A M,Emborg H D,et al.Effect of abolishment of the use of antimicrobial agents for growth promotion on occurrence of antimicrobial resistance in fecal enterococci from food animals in Denmark[J].Antimicrobial Agents and Chemotherapy,2001,45(7):2054~2059.28 Abe H,Ohya N,Yamamoto K F,et al.Effects of glycyrrhizin and glycyrrhetinic acid on growth and melanogenesis in cultured B16 melanoma cells[J].European Journal of Cancer and Clinical Oncology,1987,23(10):1549~1555.29 Aly A M,Al-Alousi L,Salem H A.Licorice:A possible anti-inflammatory and anti-ulcer drug[J].AAPS Pharm Sci Tech,2005,6(1):74~82.30 Arjumand W,Sultana S.Glycyrrhizic acid:A phytochemical with a protective role against cisplatin-induced genotoxicity and nephrotoxicity[J].Life Sciences,2011,89(13):422~429.31 Chadalapaka G,Jutooru I,McAlees A,et al.Structure-dependent inhibition of bladder and pancreatic cancer cell growth by 2-substituted glycyrrhetinic and ursolic acid derivatives[J].Bioorganic & Medicinal Chemistry Letters,2008,18(8):2633~2639.32 Eu C H,Lim W Y,Ton S H,et al.Glycyrrhizic acid improved lipoprotein lipase expression,insulin sensitivity,serum lipid and lipid deposition in high-fat diet-induced obese rats[J].Lipids Health Dis,2010,9:81.33 Fan Y,Liu J,Wang D,et al.Epimedium polysaccharide and propolis flavone can synergistically inhibit the cellular infectivity of NDV and improve the curative effect of ND in chicken[J].International Journal of Biological Macromolecules,2011,48(3):439~444.34 Hou Y Y,Yang Y,Yao Y,et al.Neuroprotection of glycyrrhizin against ischemic vascular dementia in vivo and glutamate-induced damage in vitro[J].Chin Herb Med,2010,2(2):125~131.35 Iwata K,Naito E,Yamashita K,et al.Anti pseudorabies virus activity of kumazasa extract[J].Biocontrol Science,2010,15(4):123~128.36 Kale S S,Shete R V,Kore K J.Anticonvulsant activity of glycyrrhizic acid in mice[J].Int J Pharm Res & Devel,2010,2(10):123~128.37 Kao T C,Shyu M H,Yen G C.Neuroprotective effects of glycyrrhizic acid and 18 β-glycyrrhetinic acid in PC12 cells via modulation of the PI3K/Akt pathway[J].Journal of Agricultural and Food Chemistry,2008,57(2):754~761.38 Kondratenko R M,Baltina L A,Mustafina S R,et al.The synthesis and antiviral activity of glycyrrhizic acid conjugates with α-d-glucosamine and some glycosylamines[J].Russian Journal of Bioorganic Chemistry,2004,30(3):275~282.39 Lee S C,Yang J C,Kim Y J,et al.18 β-Glyeyrrhetinie acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines[J].European Journal of Pharmacology,2010,649(1~3):1354~1361.40 Liu Y,Xiang J,Liu M,et al.Protective effects of glycyrrhizic acid by rectal treatment on a TNBS-induced rat colitis model[J].Journal of Pharmacy and Pharmacology,2011,63(3):439~446.41 Loppinet V,Visvikis S.Synthesis and in vitro antioxidant activity of glycyrrhetinic acid derivatives tested with the cytochrome P450/NADPH system[J].Chem Pharm Bull,2004,52(12):1436~1439.42 Nagai T,Egashira T,Kudo Y,et al.Attenuation of dysfunction in the ischemia-reperfused liver by glycyrrhizin[J].Japanese Journal of Pharmacology,1992,58(3):209~218.43 Niwa K,Lian Z,Onogi K,et al.Preventive effects of glycyrrhizin on estrogen-related endometrial carcinogenesis in mice[J].Oncology Reports,2007,17(3):617~622.44 Riva D A,Fernández-Larrosa P N,Dolcini G L,et al.Two immunomodulators,curcumin and sulfasalazine,enhance IDV antiretroviral activity in HIV-1 persistently infected cells[J].Archives of Virology,2008,153(3):561~565.45 Schwarz S,Csuk R.Synthesis and antitumour activity of glycyrrhetinic acid derivatives[J].Bioorganic & Medicinal Chemistry,2010,18(21):7458~7474.46 Sui X,Yin J,Ren X.Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus[J].Antiviral Research,2010,85(2):346~353.47 Thirugnanam S,Xu L,Ramaswamy K,et al.Glycyrrhizin induces apoptosis in prostate cancer cell lines DU-145 and LNCaP[J].Oncology Reports,2008,20(6):1387~1392.48 Wakamatsu T,Nakahashi Y,Hachimine D,et al.The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins[J].International Journal of Oncology,2007,31(6):1465~1472.49 Yamaguchi H,Noshita T,Yu T,et al.Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells:Induction of actin disruption and tumor cell-selective toxicity[J].European Journal of Medicinal Chemistry,2010,45(7):2943~2948.50 Yoshida T,Kobayashi M,Li X D,et al.Inhibitory effect of glycyrrhizin on the neutrophil-dependent increase of R5 HIV replication in cultures of macrophages[J].Immunology and Cell Biology,2009,87(7):554~558.51 Yu T,Yamaguchi H,Noshita T,et al.Selective cytotoxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells:Potential involvement of H-Ras downregulation[J].Toxicology Letters,2010,192(3):425~430.