过量氟对动物机体的影响

Abstract

Abstract: Fluoride is the necessary element for animal organism. Appropriate fluoride is beneficial to the growth of bones and teeth. Excessive fluoride could cause chronic systemic poisoning，which has main influence on the normal growth of bones and teeth，and also has influence on digestive system， genitourinary system，nervous system，endocrine system and immune system. According to the internal and outernal research of present situation and progresses about the mechanism of fluorosis，this paper reviews the effects of excessive fluoride on animal organism，the objective is to provide scientific reference for the related research of animal fluorosis.

Key words: fluoride; animal; fluorosis; toxicology

WANG Liang，FAN Hong-jie. Effects of Excessive Fluoride on Animal Organism[J]. .

References

1 王金明，成小芳，王俊东.氟中毒及基因组学技术在其研究中的应用［J］.中国畜牧兽医，2006，33（4）：58～60.
2 孙子龙，牛瑞燕，王俊东.氟对雄性小鼠生长发育及性腺中氟含量的影响［J］.中国畜牧兽医，2012，39（3）：227～229.
3 孙发，李崇斌，肖跃海，等.燃煤型氟中毒对雄性大鼠生殖内分泌激素的影响［J］.基础医学与临床，2011，31（10）：1077～1081.
4 张广和，李辉，韩天龙，等.氟对免疫功能的影响［J］.畜牧兽医科技信息，2013，6：7～8.
5 张京田，何立端，郝炳华，等.慢性氟中毒对大白鼠免疫功能的影响［J］.西安医科大学学报，1995，16（1）：27～29.
6 陈涛，龚涛，柏才敏，等.高氟对雏鸡法氏囊形态结构、细胞周期和凋亡影响的研究［J］.畜牧兽医学报，2009，40(8)：1235～1243.
7 杨志强，王晓亚，曹鹏，等.氟对小鼠附睾中成熟精子超微结构的影响［J］.中国畜牧兽医，2013，40（8）：137～140.
8 郭晓英，孙贵范，金亚平，等.氟对小鼠脾淋巴细胞增殖反应的影响［J］.中国地方病学杂志，2001，20（11）：32～33.
9 秦港，黎晓敏，王健.氟的生殖毒理学研究进展［J］.饲料工业，2006，27（7）：56～58.
10 续岭，谢明祥.慢性氟中毒对中枢神经系统的影响［J］.中国实用神经疾病杂志，2013，16（4）：86.
11 Al-Raddadi R M，Bahijri S M，Al-Khateeb T.1026 excessive fluoride intake is associated with hyperparathyroidism and hypothyroidism in children and adolescent，Jedda-Saudi Arabia［J］.Archives of Disease in Childhood，2012，97：A294.
12 Barbier O，Arreola-Mendoza L，Del Razo L M.Molecular mechanisms of fluoride toxicity［J］. Chemico-biological Interactions，2010，188（2）：319～333.
13 Basha P M，Rai P，Begum S.Evaluation of fluoride-induced oxidative stress in rat brain：A multigeneration study［J］.Biological Trace Element Research，2011，142（3）：623～637.
14 Choubisa S L.Status of fluorosis in animals［J］.Proceedings of the National Academy of Sciences，India Section B：Biological Sciences，2012，82（3）：331～339.
15 Ersan Y，Koc E，Ari I，et al.Histopathological effects of chronic fluorosis on the liver of mice (Swiss albino)［J］.Turk J Med Sci，2010，40(4): 619～622.
16 Everett E T.Fluoride’s effects on the formation of teeth and bones，and the influence of genetics［J］.Journal of Dental Research，2011，90（5）：552～560.
17 Hao P，Ma X，Cheng X，et al.Effect of fluoride on human hypothalamus-hypophysis-testis axis hormones［J］.Journal of Environment and Health，2009，26(4): 838～840.
18 Haque S，Pal S，Mukherjee A K，et al.Histopathological and ultramicroscopic changes induced by fluoride in soft tissue organs of the air-breathing teleost，channa punctatus (Bloch)［J］.Fluoride，2012，45(3): 263～273.
19 Hosokawa M，Asakawa H，Kaido T，et al.Deterioration of renal function in ICR-derived glomerulonephritis (ICGN) mice by subacute administration of fluoride in drinking water［J］.Fluoride，2010，43(1): 31～44.
20 Hou J X，Yang Y J，Gong B，et al.The influence of high fluoride exposure in drinking water on endocrine hormone in female［J］.Chinese Journal of Preventive Medicine，2013，47(2): 142～146.
21 Long Y G，Wang Y N，Chen J，et al.Chronic fluoride toxicity decreases the number of nicotinic acetylcholine receptors in rat brain［J］.Neurotoxicol and Teratol，2002，24: 751～757.
22 Luo Q，Cui H M，Peng X，et al.Intestinal oxidative stress in broilers caused by high dietary fluorine［J］.Fluoride，2012，45(4): 349～356.
23 Sun Z，Niu R，Wang B，et al.Fluoride-induced apoptosis and gene expression profiling in mice sperm in vivo［J］.Archives of Toxicology，2011，85(11): 1441～1452.
24 Zhou Y，Zhang H，He J，et al.Effects of sodium fluoride on reproductive function in female rats［J］.Food and Chemical Toxicology，2013，56：297～303.

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Effects of Excessive Fluoride on Animal Organism

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