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Research Progress on Virulence Factors of Acinetobacter baumannii

ZOU De-ying, LIU Dong, GUO Xing, CHEN Xiao-feng, HU Pan, LU Shi-ying, ZHOU Yu,LIU Zeng-shan, REN Hong-lin   

  1. (Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis,College of Veterinary Medicine, Jilin University, Changchun 130062, China)
  • Received:2013-08-21 Online:2014-03-20 Published:2014-05-15

Abstract: Acinetobacter baumannii is an important condition opportunistic pathogen widely distributing in human living environment. Because of its strong drug-resistant character, it has always been a hot topic in the biomedical research field. However, little knowledge of its virulence factors is known comparing to the drug-resistance research. Acinetobacter baumannii can survive for a long time in host and cause serious damage to host cells after invading the host, so virulence factors might play an important role during the invasion, proliferation and injure process. Here, we summarized the advanced researches and progresses on virulence factors of Acinetobacter baumannii for benefiting future study of its pathogenic mechanisms, providing new ideas for the potential treatment and screening drugs of diseases caused by Acinetobacter baumannii.

Key words: Acinetobacter baumannii; virulence factors; pathogenic mechanism