Abstract: This paper was conducted to investigate the effect of CC-Dp on the colts straw intake and regulation hormone in the serum.20 17-month-old healthy Yili female colts with similar body condition and intake were randomly divided into four groups and 5 colts in each group. The control group was fed with basic diet,groups Ⅰ,Ⅱ and Ⅲ were fed the basal diet supplemented with 500,1000,1500 mg/kg CC-Dp,respectively. Pre-trial period was 7 d,formally trial period was 30 d.The results showed that compared with the control group,the average straw intake in group Ⅱ was significantly increased during 1 to 15 days (P<0.05),the serum CCK and GABA contents was significantly decreased and increased during 1 to 15 days,respectively (P<0.05).Compared with the control group,the average straw intake in group Ⅲ was significantly increased in the whole period (P<0.05),the serum CCK content was extremely significantly decreased during 1 to 15 days (P<0.01),and was significantly decreased during 16 to 30 days (P<0.05),the serum GABA content was significantly increased in the whole period (P<0.05).The were no significant differences in the serum NPY,5-HT and LEP contents among all groups (P>0.05).In conclusion,the basal diet supplemented with 1500 mg/kg CC-Dp could significantly improve the straw intake,reduce the serum CCK content and increase the serum GABA content of colt. Speculated that the mechanism of CC-Dp in animal feed intake regulation was probably through reducing levels of CCK in vivo,and might be related with GABA regulatory pathways.

Key words: Yili colt; CC-Dp; straw intake; CCK; GABA